We previously reported the feasibility and efficacy of a simulation-guided clinical catheter
ablation of atrial fibrillation (AF) in an in-silico AF model. We developed a highly efficient …

Background: Recently, a new ablation strategy for atrial fibrillation has emerged, which
involves the identification of rotors (ie, local drivers) followed by the localized targeting of …

It would be clinically valuable if the efficacy of antiarrhythmic drugs could be simulated in
advance. We developed a digital twin to predict amiodarone efficacy in high-risk atrial …

Although pulmonary vein isolation (PVI) gaps and extrapulmonary vein triggers contribute to
recurrence after atrial fibrillation (AF) ablation, their precise mechanisms remain unproven …

Catheter ablation is a curative therapeutic approach for atrial fibrillation (AF). Ablation of
rotational sources based on basket catheter measurements has been proposed as a …

Background Although pulmonary vein isolation (PVI) gaps contribute to recurrence after
atrial fibrillation (AF) catheter ablation, the mechanism is unclear. We used realistic …

Background: The efficacy of antiarrhythmic drugs (AAD) can vary in patients with atrial
fibrillation (AF), and the PITX2 gene affects the responsiveness of AADs. We explored the …

Catheter ablation of critical electrical propagation sites is a promising tool for reducing the
recurrence of atrial fibrillation (AF). The spatial identification of the arrhythmogenic …

Atrial fibrillation (AF) is the most common cardiac arrhythmia and catheter mapping has
been proved to be an effective approach for detecting AF drivers to be targeted by ablation …

Introduction Although the dominant frequency (DF) localizes the reentrant drivers and the
maximal slope of the action potential duration (APD) restitution curve (Smax) reflects the …