Objective Currently, there are a lack of reviews assessing the complete range of prognostic
factors in skull base chordoma (SBC). This study aimed to systematically review the …

Introduction and objective Despite the improvements in management and treatment of
chordomas over time, the risk of disease recurrence remains high. Consequently, there is a …

Currently, little is known about the interactions between microRNAs (miRNAs) and the PD-
1/PD-L1 signaling pathway in chordoma, and data discussing the role of the immune milieu …

OBJECTIVE To characterize in situ immune cell infiltrates, the Immunoscore, and investigate
their correlation with clinicopathologic data of spinal chordoma patients and outcome …

Background: Skull base chordoma is a rare tumor with low-grade malignancy and a high
recurrence rate, the factors affecting the prognosis of patients need to be further studied. For …

Introduction Cervical cancer is a common malignancy in female and it is a serious disease
threatening women's lives. We aimed to explore whether PIF1 helicase expression could …

Study Design. Retrospective study. Objective. In this study, the authors explore the potential
relationship between hypoxia inducible factor-1α (HIF-1α) and the prognosis of patients with …

Background Spinal chordomas, a subtype of primary spinal column malignancies (PSCM),
are rare tumors with poor prognosis, and we have limited understanding of the molecular …

Purpose A chordoma is a slow-growing, invasive neoplasm in the neuraxis, thought to arise
from notochordal cells. At 10-year follow-up, the average survival rate is 50%, though the …

Background and Objective Telomerase is activated or overexpressed in 85–90% of tumors,
which maintains the length of telomere and has become an important anti-cancer target …