Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on …

P Poirier, TD Giles, GA Bray, Y Hong, JS Stern… - Circulation, 2006 - Am Heart Assoc
Obesity is becoming a global epidemic in both children and adults. It is associated with
numerous comorbidities such as cardiovascular diseases (CVD), type 2 diabetes …

Carcinoid tumors

MH Kulke, RJ Mayer - New England Journal of Medicine, 1999 - Mass Medical Soc
Carcinoid tumors were first described over 100 years ago by Lubarsch, who found multiple
tumors in the distal ileum of two patients at autopsy. 1 The term karzinoide was used by …

Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial

L Lagae, J Sullivan, K Knupp, L Laux, T Polster… - The Lancet, 2019 - thelancet.com
Background Dravet syndrome is a rare, treatment-resistant developmental epileptic
encephalopathy characterised by multiple types of frequent, disabling seizures …

Fenfluramine for treatment-resistant seizures in patients with Dravet syndrome receiving stiripentol-inclusive regimens: a randomized clinical trial

R Nabbout, A Mistry, S Zuberi, N Villeneuve… - JAMA …, 2020 - jamanetwork.com
Importance Fenfluramine treatment may reduce monthly convulsive seizure frequency in
patients with Dravet syndrome who have poor seizure control with their current stiripentol …

Evaluating medication effects outside of clinical trials: new-user designs

WA Ray - American journal of epidemiology, 2003 - academic.oup.com
Recent clinical trials demonstrating that hormone replacement therapy (HRT) does not
prevent coronary heart disease in women have again raised doubts concerning …

Investigation of the structure–activity relationships of psilocybin analogues

AK Klein, M Chatha, LJ Laskowski… - ACS pharmacology & …, 2020 - ACS Publications
The 5-HT2A receptor is thought to be the primary target for psilocybin (4-phosphoryloxy-N, N-
dimethyltryptamine) and other serotonergic hallucinogens (psychedelic drugs). Although a …

Evidence for Possible Involvement of 5-HT2B Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications

RB Rothman, MH Baumann, JE Savage, L Rauser… - Circulation, 2000 - Am Heart Assoc
Background—Serotonergic medications with various mechanisms of action are used to treat
psychiatric disorders and are being investigated as treatments for drug dependence. The …

The diagnosis and medical management of advanced neuroendocrine tumors

GA Kaltsas, GM Besser, AB Grossman - Endocrine reviews, 2004 - academic.oup.com
Neuroendocrine tumors (NETs) constitute a heterogeneous group of neoplasms that
originate from endocrine glands such as the pituitary, the parathyroids, and the …

[HTML][HTML] Dopamine agonists and the risk of cardiac-valve regurgitation

R Schade, F Andersohn, S Suissa… - … England Journal of …, 2007 - Mass Medical Soc
Background Case reports and echocardiographic studies suggest that the ergot-derived
dopamine agonists pergolide and cabergoline, used in the treatment of Parkinson's disease …

Long‐term pharmacotherapy for obesity and overweight

RS Padwal, D Rucker, SK Li… - Cochrane Database …, 2003 - cochranelibrary.com
Long‐term pharmacotherapy for obesity and overweight - Padwal, RS - 2003 | Cochrane
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