Though cell size varies between different cells and across species, the nuclear-to-
cytoplasmic (N/C) ratio is largely maintained across species and within cell types. A cell …

The mammalian embryo exhibits a remarkable plasticity that allows it to correct for the
presence of aberrant cells, adjust its growth so that its size is in accordance with its …

The evolution of embryo models | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Mammalian pre-implantation embryos accumulate substantial lipids, which are stored in
lipid droplets (LDs). Despite the fundamental roles of lipids in many cellular functions, the …

Primordial germ cells (PGCs) are the precursors of gametes and the sole mechanism by
which animals transmit genetic information across generations. In the mouse embryo, the …

Morphogenetic events during development shape the body plan and establish structural
foundations for tissue forms and functions. Acquiring spatiotemporal information of …

Using embryological data from 14 mammalian orders, the hypothesis is presented that in
placental mammals, epiblast cavitation and polar trophoblast loss are alternative …

Detailed studies of the embryo allow an increasingly mechanistic understanding of
development, which has proved of profound relevance to human disease. The last decade …

Active fluid transport across epithelial monolayers is emerging as a major driving force of
tissue morphogenesis in a variety of healthy and diseased systems, as well as during …

Pluripotent stem cells, in the recent years, have been demonstrated to mimic different
aspects of metazoan embryonic development in vitro. This has led to the establishment of …