Fibrosis progression in the lung commonly results in impaired functional gas exchange,
respiratory failure, or even death. In addition to the aberrant activation and differentiation of …

Cytokine storm generates during various systemic acute infections, including sepsis and
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …

Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …

The COVID-19 pandemic is caused by the coronavirus SARS-CoV-2 (SC2). A variety of anti-
SC2 vaccines have been approved for human applications, including those using …

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is featured by intensive
inflammatory responses and oxidative stress, which lead to cytokine storms and pyroptosis …

Abstract Background Xuanfei Baidu Formula (XBF) is an effective traditional Chinese
medicine (TCM) remedy for treating coronavirus disease 2019 (COVID-19) in China. This …

Microglia, the primary immune cells of the central nervous system (CNS), are derived from
the yolk sac and populate the brain during development. Once microglia migrate to the CNS …

Uridine metabolism is extensively reported to be involved in combating oxidative stress.
Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening
conditions triggered by multiple intra-and extra-pulmonary injury factors, characterized by …

Lung macrophages (Mφs) are essential for pulmonary innate immunity and host defense
due to their dynamic polarization and phenotype shifts. Mesenchymal stromal cells (MSCs) …