[HTML][HTML] Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules
Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
immune response. They have evolved a spectrum of immunomodulatory molecules that are …
Plasminogen activator inhibitor type‐1 as a regulator of fibrosis
R Rabieian, M Boshtam, M Zareei… - Journal of cellular …, 2018 - Wiley Online Library
Fibrosis is known as a frequent and irreversible pathological condition which is associated
with organ failure. Tissue fibrosis is a central process in a variety of chronic progressive …
with organ failure. Tissue fibrosis is a central process in a variety of chronic progressive …
The role of coagulome in the tumor immune microenvironment
The rising incidence and persistent thrombosis in multiple cancers including those that are
immunosuppressive highlight the need for understanding the tumor coagulome system and …
immunosuppressive highlight the need for understanding the tumor coagulome system and …
Synthesis, anti-proliferative activity, computational studies of tetrazole cellulose utilizing different homogenous catalyst
Micheal addition reaction of the microcrystalline cellulose (MCC)(1) with acrylonitrile (2)
afford the corresponding microcrystalline cyanoethyl cellulose (MCEC) which cyclized via …
afford the corresponding microcrystalline cyanoethyl cellulose (MCEC) which cyclized via …
[HTML][HTML] Serpin functions in host-pathogen interactions
Serpins are a broadly distributed superfamily of protease inhibitors that are present in all
kingdoms of life. The acronym, serpin, is derived from their function as potent ser ine p …
kingdoms of life. The acronym, serpin, is derived from their function as potent ser ine p …
[HTML][HTML] Fibrinolytic serine proteases, therapeutic serpins and inflammation: fire dancers and firestorms
The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine
protease cascades are critical determinants of morbidity and mortality during infection and …
protease cascades are critical determinants of morbidity and mortality during infection and …
Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets
RA Jacobson, K Wienholts… - American Journal …, 2020 - journals.physiology.org
Perforations, anastomotic leak, and subsequent intra-abdominal sepsis are among the most
common and feared complications of invasive interventions in the colon and remaining …
common and feared complications of invasive interventions in the colon and remaining …
[HTML][HTML] Therapeutic SERPINs: improving on nature
Serine proteases drive important physiological processes such as coagulation, fibrinolysis,
inflammation and angiogenesis. These proteases are controlled by serine protease …
inflammation and angiogenesis. These proteases are controlled by serine protease …
Physiological and pathological functions of neuroserpin: regulation of cellular responses through multiple mechanisms
It is 27 years since neuroserpin was first discovered in the nervous system and identified as
a member of the serpin superfamily. Since that time potential roles for this serine protease …
a member of the serpin superfamily. Since that time potential roles for this serine protease …
[HTML][HTML] Immune protection is dependent on the gut microbiome in a lethal mouse gammaherpesviral infection
Immunopathogenesis in systemic viral infections can induce a septic state with leaky
capillary syndrome, disseminated coagulopathy, and high mortality with limited treatment …
capillary syndrome, disseminated coagulopathy, and high mortality with limited treatment …