Tumor metastasis remains the principal cause of treatment failure and poor prognosis in
patients with colorectal cancer. It is a multistage process which includes proteolysis, motility …

Background Increased mesenchymal–epithelial transition factor gene (c-MET) expression in
several human malignancies is related to increased tumour progression. The aim of the …

Background: CD133 and CD44 are putative cancer stem cell (CSC) markers in colorectal
cancer (CRC). However, their clinical significance is currently unclear. Here, we evaluated …

Background To investigate the relationship of KAI1/CD82, CD44, matrix metalloproteinase 7
(MMP7) and β-catenin, and examine its association with clinicopathological features …

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths among both
men and women in the United States. Early detection and surgical removal of high-risk …

Stratification of colorectal cancer for better management and tangible clinical outcomes is
lacking in clinical practice. To reach this goal, the identification of reliable biomarker (s) is a …

The loss of adhesion molecules is reported to be associated with tumor invasion and
metastasis in numerous types of cancer. Epithelial (E)‑cadherin is an important molecule for …

Objectives The aim of this work was to study the immunohistochemical expression of CD44
in colorectal carcinoma (CRC) cases. Background Cancer stem cells (CSCs) have a role in …

CD44 is a transmembrane glycoprotein and is regarded as a potential marker in various
tumors. The aim of our study was to analyze the expression of the standard form of CD44 …

Background and study aims Colorectal carcinoma (CRC) is associated with high morbidity
and mortality. The E-cadherin–catenin complex is crucial in the development and …