The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks

R Enaud, R Prevel, E Ciarlo, F Beaufils… - Frontiers in cellular …, 2020 - frontiersin.org
The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …

The human respiratory system and its microbiome at a glimpse

L Santacroce, IA Charitos, A Ballini, F Inchingolo… - Biology, 2020 - mdpi.com
Simple Summary New data in the current scientific literature show that the composition of the
respiratory system microbiome differs in health and disease conditions and that the …

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

AY Bhagirath, Y Li, D Somayajula, M Dadashi… - BMC pulmonary …, 2016 - Springer
Background The airways of patients with cystic fibrosis (CF) are highly complex, subject to
various environmental conditions as well as a distinct microbiota. Pseudomonas aeruginosa …

Oral Prevotella Species and Their Connection to Events of Clinical Relevance in Gastrointestinal and Respiratory Tracts

E Könönen, UK Gursoy - Frontiers in microbiology, 2022 - frontiersin.org
Prevotella is recognized as one of the core anaerobic genera in the oral microbiome. In
addition, members of this genus belong to microbial communities of the gastrointestinal and …

Airway microbiota across age and disease spectrum in cystic fibrosis

ET Zemanick, BD Wagner… - European …, 2017 - Eur Respiratory Soc
Our objectives were to characterise the microbiota in cystic fibrosis (CF) bronchoalveolar
lavage fluid (BALF), and determine its relationship to inflammation and disease status. BALF …

Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

MS Muhlebach, BT Zorn, CR Esther, JE Hatch… - PLoS …, 2018 - journals.plos.org
The cystic fibrosis (CF) lung microbiome has been studied in children and adults; however,
little is known about its relationship to early disease progression. To better understand the …

The microbiome in cystic fibrosis

YJ Huang, JJ LiPuma - Clinics in chest medicine, 2016 - chestmed.theclinics.com
Recent elucidation of the richness and complexity of the microbiome in patients with cystic
fibrosis (CF) has invigorated new discussions of the role of microbial infection in CF beyond …

Bolus Weekly Vitamin D3 Supplementation Impacts Gut and Airway Microbiota in Adults With Cystic Fibrosis: A Double-Blind, Randomized, Placebo-Controlled …

M Kanhere, J He, B Chassaing… - The Journal of …, 2018 - academic.oup.com
Context Disruption of gut microbiota may exacerbate severity of cystic fibrosis (CF). Vitamin
D deficiency is a common comorbidity in patients with CF that may influence composition of …

Co-colonisation with Aspergillus fumigatus and Pseudomonas aeruginosa is associated with poorer health in cystic fibrosis patients: an Irish registry analysis

E Reece, R Segurado, A Jackson, S McClean… - BMC pulmonary …, 2017 - Springer
Background Pulmonary infection is the main cause of death in cystic fibrosis (CF).
Aspergillus fumigatus (AF) and Pseudomonas aeruginosa (PA) are the most prevalent …

The lower airway microbiota in early cystic fibrosis lung disease: a longitudinal analysis

KB Frayman, DS Armstrong, R Carzino, TW Ferkol… - Thorax, 2017 - thorax.bmj.com
Rationale In infants and young children with cystic fibrosis, lower airway infection and
inflammation are associated with adverse respiratory outcomes. However, the role of lower …