Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal
cancers, with a five-year survival rate of around 5% to 8%. To date, very few available drugs …

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC).
PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are …

METHODS: This multicenter cohort study consisted of patients undergoing endoscopic
ultrasound–guided fine-needle aspiration (EUS-FNA) for pancreatic cysts during January …

In humans, the UDP-N-α-D galactosamine: polypeptide N-acetylgalactosaminyltransferases
family (ppGalNAc-Ts, GalNAc-Ts or GALNTs) comprises 20 isoenzymes. They are …

There is increasing evidence suggesting the role of microbiome alterations in relation to
pancreatic adenocarcinoma and tumor immune functionality. However, molecular …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive regression and memory loss. Dysfunctions of both glucose metabolism and …

There has been a surge of interest in recent years in understanding the intricate
mechanisms underlying cancer progression and treatment resistance. One molecule that …

Mucins are high-molecular-weight glycoproteins dysregulated in aggressive cancers. The
role of mucins in disease progression, tumor proliferation, and chemotherapy resistance has …

Anchorage-independent survival after intravasation of cancer cells from the primary tumor
site represents a critical step in metastasis. Here, we reveal new insights into how MUC13 …

Big data analysis holds a considerable influence on several aspects of biomedical health
science. It permits healthcare providers to gain insights from large and complex datasets …