How the PhoP/PhoQ System Controls Virulence and Mg2+ Homeostasis: Lessons in Signal Transduction, Pathogenesis, Physiology, and Evolution

EA Groisman, A Duprey, J Choi - Microbiology and Molecular …, 2021 - Am Soc Microbiol
SUMMARY The PhoP/PhoQ two-component system governs virulence, Mg2+ homeostasis,
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …

RNA-binding proteins in bacteria

E Holmqvist, J Vogel - Nature Reviews Microbiology, 2018 - nature.com
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the
fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal …

RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12

VH Tierrafría, C Rioualen, H Salgado… - Microbial …, 2022 - microbiologyresearch.org
Genomics has set the basis for a variety of methodologies that produce high-throughput
datasets identifying the different players that define gene regulation, particularly regulation …

Global regulation by CsrA and its RNA antagonists

T Romeo, P Babitzke - Microbiology spectrum, 2018 - Am Soc Microbiol
The sequence-specific RNA binding protein CsrA is employed by diverse bacteria in the
posttranscriptional regulation of gene expression. Its binding interactions with RNA have …

Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics

AH Potts, CA Vakulskas, A Pannuri, H Yakhnin… - Nature …, 2017 - nature.com
CsrA is a post-transcriptional regulatory protein that is widely distributed among bacteria.
This protein influences bacterial lifestyle decisions by binding to the 5′ untranslated and/or …

Diverse mechanisms and circuitry for global regulation by the RNA-binding protein CsrA

C Pourciau, YJ Lai, M Gorelik, P Babitzke… - Frontiers in …, 2020 - frontiersin.org
The carbon storage regulator (Csr) or repressor of stationary phase metabolites (Rsm)
system of Gammaproteobacteria is among the most complex and best-studied …

The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar …

AM Colgan, C Kröger, M Diard, WD Hardt… - PLoS …, 2016 - journals.plos.org
We know a great deal about the genes used by the model pathogen Salmonella enterica
serovar Typhimurium to cause disease, but less about global gene regulation. New tools for …

A comparative whole-genome approach identifies bacterial traits for marine microbial interactions

L Zoccarato, D Sher, T Miki, D Segrè… - Communications …, 2022 - nature.com
Microbial interactions shape the structure and function of microbial communities with
profound consequences for biogeochemical cycles and ecosystem health. Yet, most …

Insights into the resistome of bovine clinical mastitis microbiome, a key factor in disease complication

MN Hoque, A Istiaq, RA Clement, KM Gibson… - Frontiers in …, 2020 - frontiersin.org
Bovine clinical mastitis (CM) is one of the most prevalent diseases caused by a wide range
of resident microbes. The emergence of antimicrobial resistance in CM bacteria is well …

Involvement of two-component signaling on bacterial motility and biofilm development

BM Prüß - Journal of bacteriology, 2017 - Am Soc Microbiol
Two-component signaling is a specialized mechanism that bacteria use to respond to
changes in their environment. Nonpathogenic strains of Escherichia coli K-12 harbor 30 …