The purpose of this review article is to give an overview of atopic dermatitis in companion
animals and of recent developments including knowledge on immunological background …

During the last decades, high-throughput assessment of gene expression in patient tissues
using microarray technology or RNA-Seq took center stage in clinical research. Insights into …

Chronic allergic itch is a common symptom affecting millions of people and animals, but its
pathogenesis is not fully explained. Herein, we show that periostin, abundantly expressed in …

Background Multiple levels of evidence support the role of genetics and the environment in
the pathogenesis of canine atopic dermatitis (AD). Objectives This review summarizes the …

Background The development of atopic dermatitis (AD) and other cutaneous
hypersensitivities involves the activation and differentiation of allergen‐specific lymphocytes …

Background Canine atopic dermatitis (cAD) is a common chronic and pruritic skin disease in
dogs. The development of cAD involves complex interactions between environmental …

Recent studies have shown that immunological aberrations and epidermal barrier defects
could be important in the pathogenesis of canine atopic dermatitis (CAD) and that oral …

Traditionally, keratinocytes have been considered inert constituents of the multilayered
epidermis. Today's understanding has fundamentally changed. The keratinocyte is now …

Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease caused by complex
interactions between genetics and environmental factors. In human beings, impairment of …

BACKGROUND: Canine atopic dermatitis (cAD) is a common condition in dogs that may be
a naturally occurring model for human atopic dermatitis (hAD). Despite this, comparative …