State of the art: pharmacologic effects on cortical excitability measures tested by transcranial magnetic stimulation

W Paulus, J Classen, LG Cohen, CH Large… - Brain stimulation, 2008 - Elsevier
The combination of brain stimulation techniques like transcranial magnetic stimulation (TMS)
with CNS active drugs in humans now offers a unique opportunity to explore the physiologic …

Restless legs syndrome: pathophysiology, clinical presentation and management

C Trenkwalder, W Paulus - Nature Reviews Neurology, 2010 - nature.com
Restless legs syndrome (RLS) is a somatosensory network disorder that is clinically
diagnosed according to four main criteria: an urge to move the legs, usually associated with …

Neuromodulation in Tourette syndrome: dopamine and beyond

J Buse, K Schoenefeld, A Münchau… - … & Biobehavioral Reviews, 2013 - Elsevier
Almost since the beginning of research on Tourette syndrome (TS), tics have been linked to
a dysfunction of the dopamine (DA) system. At first, this assumption was mainly based on …

Dissociation of periodic leg movements from arousals in restless legs syndrome

M Manconi, R Ferri, M Zucconi, CL Bassetti… - Annals of …, 2012 - Wiley Online Library
Objective: The purpose of this study was to characterize the nature of the relation between
periodic leg movements during sleep (PLMS) and cortical arousals to contribute to the …

Central and peripheral nervous system excitability in restless legs syndrome

G Lanza, CG Bachmann, I Ghorayeb, Y Wang, R Ferri… - Sleep medicine, 2017 - Elsevier
Neurophysiological techniques have been applied in restless legs syndrome (RLS) to obtain
direct and indirect measures of central and peripheral nervous system excitability, as well as …

Distinctive patterns of cortical excitability to transcranial magnetic stimulation in obstructive sleep apnea syndrome, restless legs syndrome, insomnia, and sleep …

G Lanza, M Cantone, B Lanuzza, M Pennisi… - Sleep medicine …, 2015 - Elsevier
Altered responses to transcranial magnetic stimulation (TMS) in obstructive sleep apnea
syndrome (OSAS), restless legs syndrome (RLS), insomnia, and sleep-deprived healthy …

Dopamine D2-agonist Rotigotine effects on cortical excitability and central cholinergic transmission in Alzheimer's disease patients

A Martorana, F Di Lorenzo, Z Esposito, TL Giudice… - …, 2013 - Elsevier
Dopamine is a neurotransmitter involved in several brain functions ranging from emotions
control, movement organization to memory formation. It is also involved in the regulation of …

Restless legs syndrome—current therapies and management of augmentation

C Trenkwalder, J Winkelmann, Y Inoue… - Nature Reviews …, 2015 - nature.com
Idiopathic restless legs syndrome (RLS) can severely affect quality of life and disturb sleep,
so that pharmacological treatment is necessary, especially for elderly patients. Treatment …

Restless legs syndrome and periodic leg movements of sleep

DB Rye, LM Trotti - Neurologic clinics, 2012 - neurologic.theclinics.com
Restless legs syndrome (RLS) is defined by a compelling urge to move the legs that
worsens with inactivity, is relieved by movement or counterstimuli, and is most aggravating …

Direct comparison of cortical excitability to transcranial magnetic stimulation in obstructive sleep apnea syndrome and restless legs syndrome

G Lanza, B Lanuzza, D Aricò, M Cantone, FII Cosentino… - Sleep medicine, 2015 - Elsevier
Objective Changes to transcranial magnetic stimulation (TMS) have been reported in
obstructive sleep apnea syndrome (OSAS) and restless legs syndrome (RLS), although no …