Many cancer patients treated with chemotherapy develop chemotherapy-induced cognitive
impairment (CICI), often referred to as chemo-brain, which manifest during or post-treatment …

Taxane‐derived drugs are antineoplastic agents used for the treatment of highly common
malignancies. Paclitaxel and docetaxel are the most commonly used taxanes; however …

BACKGROUND: Growing evidence supports cognitive dysfunction associated with standard
dose chemotherapy in breast cancer survivors. We determined the incidence, nature, and …

Central and peripheral nervous system toxicity are frequent complications of most
chemotherapy regimens, often leading to reduction of dosages or cessation of the …

Paclitaxel (PTX) is one of the most broadly used chemotherapeutic agents for the treatment
of several tumor types including ovarian, breast, and non-small cell lung cancer. However …

Purpose To investigate symptom severity, symptom cluster trajectories and sentinel
symptoms during chemotherapy cycle 1 in patients with lung cancer. Methods Patients with …

Historically, body tissues with a high rate of cell turnover, such as the bone marrow, have
been most susceptible to chemotherapy-induced damage. The widespread use of …

Chemotherapy-induced central nervous system (CNS) neurotoxicity presents an unmet
medical need. Patients often report a cognitive decline in temporal correlation to …

Delirium is a complex syndrome with a multifactorial aetiology and is characterized by
marked disturbances of consciousness, attention, memory, perception, thought, sleep-wake …

The development of paclitaxel-loaded polymeric nanoparticles for the treatment of brain
tumors was investigated. Poly (lactide-glycolide)(PLGA) nanoparticles containing 10% w/w …