Bidirectional learning in upbound and downbound microzones of the cerebellum
CI De Zeeuw - Nature Reviews Neuroscience, 2021 - nature.com
Over the past several decades, theories about cerebellar learning have evolved. A relatively
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …
Imaging whole-brain activity to understand behaviour
Until now, most brain studies have focused on small numbers of neurons that interact in
limited circuits, allowing analysis of individual computations or steps of neural processing …
limited circuits, allowing analysis of individual computations or steps of neural processing …
High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy
Two-photon microscopy has enabled high-resolution imaging of neuroactivity at depth within
scattering brain tissue. However, its various realizations have not overcome the tradeoffs …
scattering brain tissue. However, its various realizations have not overcome the tradeoffs …
[HTML][HTML] Iterative tomography with digital adaptive optics permits hour-long intravital observation of 3D subcellular dynamics at millisecond scale
Long-term subcellular intravital imaging in mammals is vital to study diverse intercellular
behaviors and organelle functions during native physiological processes. However, optical …
behaviors and organelle functions during native physiological processes. However, optical …
Cognitive-affective functions of the cerebellum
The cerebellum, traditionally associated with motor coordination and balance, also plays a
crucial role in various aspects of higher-order function and dysfunction. Emerging research …
crucial role in various aspects of higher-order function and dysfunction. Emerging research …
[HTML][HTML] Computational optical sectioning with an incoherent multiscale scattering model for light-field microscopy
Quantitative volumetric fluorescence imaging at high speed across a long term is vital to
understand various cellular and subcellular behaviors in living organisms. Light-field …
understand various cellular and subcellular behaviors in living organisms. Light-field …
[HTML][HTML] A brainstem integrator for self-location memory and positional homeostasis in zebrafish
To track and control self-location, animals integrate their movements through space.
Representations of self-location are observed in the mammalian hippocampal formation, but …
Representations of self-location are observed in the mammalian hippocampal formation, but …
Deep learning-enhanced light-field imaging with continuous validation
N Wagner, F Beuttenmueller, N Norlin, J Gierten… - Nature …, 2021 - nature.com
Visualizing dynamic processes over large, three-dimensional fields of view at high speed is
essential for many applications in the life sciences. Light-field microscopy (LFM) has …
essential for many applications in the life sciences. Light-field microscopy (LFM) has …
[HTML][HTML] Precise visuomotor transformations underlying collective behavior in larval zebrafish
Complex schooling behaviors result from local interactions among individuals. Yet, how
sensory signals from neighbors are analyzed in the visuomotor stream of animals is poorly …
sensory signals from neighbors are analyzed in the visuomotor stream of animals is poorly …
Regional synapse gain and loss accompany memory formation in larval zebrafish
WP Dempsey, Z Du, A Nadtochiy… - Proceedings of the …, 2022 - National Acad Sciences
Defining the structural and functional changes in the nervous system underlying learning
and memory represents a major challenge for modern neuroscience. Although changes in …
and memory represents a major challenge for modern neuroscience. Although changes in …