[HTML][HTML] Withania somnifera L.: Insights into the phytochemical profile, therapeutic potential, clinical trials, and future prospective
Withania somnifera L. is a multipurpose medicinal plant of family Solanaceae occurring
abundantly in sub-tropical regions of the world. The folk healers used the plant to treat …
abundantly in sub-tropical regions of the world. The folk healers used the plant to treat …
Natural plants compounds as modulators of epithelial-to-mesenchymal transition
L Avila-Carrasco, P Majano… - Frontiers in …, 2019 - frontiersin.org
Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …
required for tissue repair that, in non-controled conditions may lead to fibrosis …
Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor
SARS-CoV-2 is the causative agent of COVID-19 and has been declared as pandemic
disease by World Health Organization. Lack of targeted therapeutics and vaccines for …
disease by World Health Organization. Lack of targeted therapeutics and vaccines for …
Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish …
Purpose SARS-CoV-2 engages human ACE2 through its spike (S) protein receptor binding
domain (RBD) to enter the host cell. Recent computational studies have reported that …
domain (RBD) to enter the host cell. Recent computational studies have reported that …
Botanical ingredient forensics: detection of attempts to deceive commonly used analytical methods for authenticating herbal dietary and food ingredients and …
S Gafner, M Blumenthal, S Foster… - Journal of Natural …, 2023 - ACS Publications
Botanical ingredients are used widely in phytomedicines, dietary/food supplements,
functional foods, and cosmetics. Products containing botanical ingredients are popular …
functional foods, and cosmetics. Products containing botanical ingredients are popular …
Green and cost effective synthesis of silver nanoparticles from endangered medicinal plant Withania coagulans and their potential biomedical properties
Silver nanoparticles (AgNPs) have great potential for their mechanistic role in biomedical
researches. Recently, green biosynthetic approaches have been received much attention in …
researches. Recently, green biosynthetic approaches have been received much attention in …
Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments
N Tandon, SS Yadav - Journal of Ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Withania somnifera popularly known as Aswagandha or
Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian …
Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian …
Withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
JT Thaiparambil, L Bender, T Ganesh… - … journal of cancer, 2011 - Wiley Online Library
Withaferin A (WFA) is purified from the plant Withania somnifera and inhibits the vimentin
cytoskeleton. Vimentin overexpression in cancer correlates with metastatic disease …
cytoskeleton. Vimentin overexpression in cancer correlates with metastatic disease …
Withanone from Withania somnifera may inhibit novel coronavirus (COVID-19) entry by disrupting interactions between viral S-protein receptor binding domain and …
Background Newly emerged COVID-19 has been shown to engage the host cell ACE2
through its spike protein receptor binding domain (RBD). Here we show that natural …
through its spike protein receptor binding domain (RBD). Here we show that natural …
Comprehensive metabolic fingerprinting of Withania somnifera leaf and root extracts
S Chatterjee, S Srivastava, A Khalid, N Singh… - Phytochemistry, 2010 - Elsevier
Profiling of metabolites is a rapidly expanding area of research for resolving metabolic
pathways. Metabolic fingerprinting in medicinally important plants is critical to establishing …
pathways. Metabolic fingerprinting in medicinally important plants is critical to establishing …