Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Certain neurons in the mammalian brain have long been known to be joined by gap
junctions, which are the most common type of electrical synapse. More recently, cloning of …

▪ Abstract Many neurons in the mammalian central nervous system communicate through
electrical synapses, defined here as gap junction–mediated connections. Electrical …

Database search has led to the identification of a family of proteins, the pannexins, which
share some structural features with the gap junction forming proteins of invertebrates and …

Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …

Cerebellar reserve refers to the capacity of the cerebellum to compensate for tissue damage
or loss of function resulting from many different etiologies. When the inciting event produces …

Electrical synapses are found in vertebrate and invertebrate nervous systems. The cellular
basis of these synapses is the gap junction, a group of intercellular channels that mediate …

Gap junctions are channel-forming structures in contacting plasma membranes that allow
direct metabolic and electrical communication between almost all cell types in the …