Extracellular vesicles as a next-generation drug delivery platform
IK Herrmann, MJA Wood, G Fuhrmann - Nature nanotechnology, 2021 - nature.com
Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
[HTML][HTML] Engineering exosomes for targeted drug delivery
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …
Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications
J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …
are natural nanocarriers secreted by various cells, making them suitable candidates for …
Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer
Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
Peroxidase-like active nanomedicine with dual glutathione depletion property to restore oxaliplatin chemosensitivity and promote programmed cell death
F Wu, Y Du, J Yang, B Shao, Z Mi, Y Yao, Y Cui, F He… - ACS …, 2022 - ACS Publications
The nanocatalytic activity of nanozymes provides a vision for tumor treatment. However, the
glutathione (GSH)-related antioxidant defense system (ADS) formed on the basis of …
glutathione (GSH)-related antioxidant defense system (ADS) formed on the basis of …
Liposomes and extracellular vesicles as drug delivery systems: A comparison of composition, pharmacokinetics, and functionalization
L van der Koog, TB Gandek… - Advanced healthcare …, 2022 - Wiley Online Library
Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer …
L Cheng, X Zhang, J Tang, Q Lv, J Liu - Biomaterials, 2021 - Elsevier
CD47, overexpressed on kinds of tumor cells, activates a “don't eat me” signal through
binding to signal regulatory protein α (SIRPα), leading to immune escape from the …
binding to signal regulatory protein α (SIRPα), leading to immune escape from the …
Extracellular vesicles: A bright star of nanomedicine
P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …
characteristics as well as predominant physiochemical stability and biocompatibility …
Extracellular vesicles: a rising star for therapeutics and drug delivery
S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …