Specific expression and functions of circular RNAs
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …
their covalently closed circular structure, have become a new research paradigm in RNA …
Targeting circular RNAs as a therapeutic approach: current strategies and challenges
Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
CircRNAs: role in human diseases and potential use as biomarkers
L Verduci, E Tarcitano, S Strano, Y Yarden… - Cell death & …, 2021 - nature.com
Circular RNAs (circRNAs) are a class of endogenous RNAs characterized by a covalent
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …
loop structure. In comparison to other types of RNAs, the abundance of circRNAs is relatively …
Circular RNA and its mechanisms in disease: from the bench to the clinic
B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …
to a new perspective regarding our understanding of cellular physiology and disease …
Circular RNA in cardiovascular disease
MA Altesha, T Ni, A Khan, K Liu… - Journal of cellular …, 2019 - Wiley Online Library
Circular RNA (circRNA) are endogenous transcripts that display differential expression
across species, developmental stages, and pathologies. Their lack of free ends confers …
across species, developmental stages, and pathologies. Their lack of free ends confers …
CircRNAs and cancer: biomarkers and master regulators
E Arnaiz, C Sole, L Manterola, L Iparraguirre… - Seminars in cancer …, 2019 - Elsevier
Circular RNAs (circRNAs) are a novel class of regulatory RNAs that despite being relatively
abundant have only recently begun to be explored. There are many thousands of genes that …
abundant have only recently begun to be explored. There are many thousands of genes that …
Circular RNAs open a new chapter in cardiovascular biology
S Aufiero, YJ Reckman, YM Pinto… - Nature Reviews …, 2019 - nature.com
Circular RNAs (circRNAs) are emerging as a new class of non-coding RNA molecules. This
unusual class of RNA species is generated by a back-splicing event of one or two exons …
unusual class of RNA species is generated by a back-splicing event of one or two exons …
Circular RNAs: biogenesis, function and role in human diseases
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
linear RNAs, form covalently closed continuous loops and act as gene regulators in …
Circular RNAs in kidney disease and cancer
Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a
single-stranded circular structure. They are generated by back splicing and their expression …
single-stranded circular structure. They are generated by back splicing and their expression …
RNA-based diagnostic and therapeutic strategies for cardiovascular disease
D Lu, T Thum - Nature Reviews Cardiology, 2019 - nature.com
Cardiovascular diseases are the leading cause of death globally and are associated with
increasing financial expenditure. With the availability of next-generation sequencing …
increasing financial expenditure. With the availability of next-generation sequencing …