Despite the importance of microbial natural products for human health, only a few bacterial
genera have been mined for the new natural products needed to overcome the urgent threat …

Covering: up to November 2017 Organismic interaction is one of the fundamental principles
for survival in any ecosystem. Today, numerous examples show the interaction between …

Covering: up to the end of 2020 Nonribosomal peptide synthetases are remarkable
molecular machines that produce a wide range of structurally complex peptide natural …

Covering: up to 2017 The overwhelming majority of antibiotics in clinical use originate from
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …

Parasitic nematodes infect different species of animals and plants. Root-knot nematodes are
members of the genus Meloidogyne, which is distributed worldwide and parasitizes …

Background The biological diversity on planet earth is declining day by day, due to different
factors such as excessive applications of pesticides. The utilization of chemical pesticides …

Mounting concern over the misuse of chemical pesticides has sparked broad interest for
safe and effective alternatives to control plant pests and pathogens. Xenorhabdus bacteria …

Natural products have been proven to be important starting points for the development of
new drugs. Bacteria in the genera Photorhabdus and Xenorhabdus produce antimicrobial …

Abstract Non-Ribosomal Peptides (NRPs) represent a biomedically important class of
natural products that include a multitude of antibiotics and other clinically used drugs. NRPs …

The production of natural product compound libraries has been observed in nature for
different organisms such as bacteria, fungi and plants; however, little is known about the …