The mechanosensory neurons of touch and their mechanisms of activation
Our sense of touch emerges from an array of mechanosensory structures residing within the
fabric of our skin. These tactile end organ structures convert innocuous forces acting on the …
fabric of our skin. These tactile end organ structures convert innocuous forces acting on the …
The sensory neurons of touch
VE Abraira, DD Ginty - neuron, 2013 - cell.com
The somatosensory system decodes a wide range of tactile stimuli and thus endows us with
a remarkable capacity for object recognition, texture discrimination, sensory-motor feedback …
a remarkable capacity for object recognition, texture discrimination, sensory-motor feedback …
The gentle touch receptors of mammalian skin
A Zimmerman, L Bai, DD Ginty - Science, 2014 - science.org
The skin is our largest sensory organ, transmitting pain, temperature, itch, and touch
information to the central nervous system. Touch sensations are conveyed by distinct …
information to the central nervous system. Touch sensations are conveyed by distinct …
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
S Maksimovic, M Nakatani, Y Baba, AM Nelson… - Nature, 2014 - nature.com
Touch submodalities, such as flutter and pressure, are mediated by somatosensory afferents
whose terminal specializations extract tactile features and encode them as action potential …
whose terminal specializations extract tactile features and encode them as action potential …
[HTML][HTML] The functional organization of cutaneous low-threshold mechanosensory neurons
L Li, M Rutlin, VE Abraira, C Cassidy, L Kus, S Gong… - Cell, 2011 - cell.com
Innocuous touch of the skin is detected by distinct populations of neurons, the low-threshold
mechanoreceptors (LTMRs), which are classified as Aβ-, Aδ-, and C-LTMRs. Here, we report …
mechanoreceptors (LTMRs), which are classified as Aβ-, Aδ-, and C-LTMRs. Here, we report …
The cellular and molecular basis of somatosensory neuron development
Primary somatosensory neurons convey salient information about our external environment
and internal state to the CNS, allowing us to detect, perceive, and react to a wide range of …
and internal state to the CNS, allowing us to detect, perceive, and react to a wide range of …
Molecular mechanisms of mechanotransduction in mammalian sensory neurons
P Delmas, J Hao, L Rodat-Despoix - Nature Reviews Neuroscience, 2011 - nature.com
The somatosensory system mediates fundamental physiological functions, including the
senses of touch, pain and proprioception. This variety of functions is matched by a diverse …
senses of touch, pain and proprioception. This variety of functions is matched by a diverse …
Merkel cells are essential for light-touch responses
SM Maricich, SA Wellnitz, AM Nelson, DR Lesniak… - Science, 2009 - science.org
The peripheral nervous system detects different somatosensory stimuli, including pain,
temperature, and touch. Merkel cell-neurite complexes are touch receptors composed of …
temperature, and touch. Merkel cell-neurite complexes are touch receptors composed of …
The cellular and molecular basis of direction selectivity of Aδ-LTMRs
M Rutlin, CY Ho, VE Abraira, C Cassidy, L Bai… - Cell, 2014 - cell.com
The perception of touch, including the direction of stimulus movement across the skin,
begins with activation of low-threshold mechanosensory neurons (LTMRs) that innervate the …
begins with activation of low-threshold mechanosensory neurons (LTMRs) that innervate the …
The benefit of combined acupuncture and antidepressant medication for depression: a systematic review and meta-analysis
YY Chan, WY Lo, SN Yang, YH Chen, JG Lin - Journal of Affective …, 2015 - Elsevier
Acupuncture, one of the most popular complementary therapies, is best known for its ability
to provide pain relief. Accumulating evidence suggests that acupuncture may also be …
to provide pain relief. Accumulating evidence suggests that acupuncture may also be …