Recent progress in nanotechnology-based drug carriers for resveratrol delivery
C Li, Z Wang, H Lei, D Zhang - Drug delivery, 2023 - Taylor & Francis
Resveratrol is a polyphenol with diverse pharmacological activities, but its clinical efficacy is
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
Inflammation, lifestyle factors, and the microbiome‐gut‐brain Axis: relevance to depression and antidepressant action
Depression is considered a major public health concern, where existing pharmacological
treatments are not equally effective across all patients. The pathogenesis of depression …
treatments are not equally effective across all patients. The pathogenesis of depression …
Insulin resistance and diabetes mellitus in Alzheimer's disease
Type 2 diabetes mellitus is a progressive disease that is characterized by the appearance of
insulin resistance. The term insulin resistance is very wide and could affect different proteins …
insulin resistance. The term insulin resistance is very wide and could affect different proteins …
Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
The neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and …
MS Karvandi, F Sheikhzadeh Hesari… - Frontiers in Cellular …, 2023 - frontiersin.org
Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …
Sustainable drug discovery of multi-target-directed ligands for Alzheimer's disease
M Rossi, M Freschi… - Journal of medicinal …, 2021 - ACS Publications
The multifactorial nature of Alzheimer's disease (AD) is a reason for the lack of effective
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …
A mosquito salivary protein-driven influx of myeloid cells facilitates flavivirus transmission
Z Wang, K Nie, Y Liang, J Niu, X Yu, O Zhang… - The EMBO …, 2024 - embopress.org
Mosquitoes transmit many disease-relevant flaviviruses. Efficient viral transmission to
mammalian hosts requires mosquito salivary factors. However, the specific salivary …
mammalian hosts requires mosquito salivary factors. However, the specific salivary …
Natural products for the treatment of neurodegenerative diseases
D Cui, Y Chen, B Ye, W Guo, D Wang, J He - Phytomedicine, 2023 - Elsevier
Background Neurodegenerative diseases are among the most common diseases in older
adults worldwide. Alzheimer's disease (AD) and Parkinson's disease (PD) are two of the …
adults worldwide. Alzheimer's disease (AD) and Parkinson's disease (PD) are two of the …
[HTML][HTML] Oxidative stress, the blood–brain barrier and neurodegenerative diseases: The critical beneficial role of dietary antioxidants
J Feng, Y Zheng, M Guo, I Ares, M Martínez… - … Pharmaceutica Sinica B, 2023 - Elsevier
In recent years, growing awareness of the role of oxidative stress in brain health has
prompted antioxidants, especially dietary antioxidants, to receive growing attention as …
prompted antioxidants, especially dietary antioxidants, to receive growing attention as …