Base excision repair: a critical player in many games
SS Wallace - DNA repair, 2014 - Elsevier
This perspective reviews the many dimensions of base excision repair from a 10,000 foot
vantage point and provides one person's view on where the field is headed. Enzyme …
vantage point and provides one person's view on where the field is headed. Enzyme …
MUTYH-associated tumor syndrome: The other face of MAP
L Magrin, D Fanale, C Brando, LR Corsini, U Randazzo… - Oncogene, 2022 - nature.com
MUTYH gene is involved in the base excision repair (BER) mechanism and its pathogenic
alterations are associated with colorectal polyposis and cancer. MUTYH-associated …
alterations are associated with colorectal polyposis and cancer. MUTYH-associated …
LAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy
T Saha - Autophagy, 2012 - Taylor & Francis
Lysosome-associated membrane protein type 2A (LAMP2A) is a key protein in the
chaperone-mediated autophagy (CMA) pathway. LAMP2A helps in lysosomal uptake of …
chaperone-mediated autophagy (CMA) pathway. LAMP2A helps in lysosomal uptake of …
BRCA1 in the DNA damage response and at telomeres
EM Rosen - Frontiers in genetics, 2013 - frontiersin.org
Mutations of the breast and ovarian cancer susceptibility gene 1 (BRCA1) account for about
40–45% of hereditary breast cancer cases. Moreover, a significant fraction of sporadic (non …
40–45% of hereditary breast cancer cases. Moreover, a significant fraction of sporadic (non …
Regulation of DNA glycosylases and their role in limiting disease
H Sampath, AK McCullough, RS Lloyd - Free radical research, 2012 - Taylor & Francis
Full article: Regulation of DNA glycosylases and their role in limiting disease Skip to Main
Content Taylor and Francis Online homepage Taylor and Francis Online homepage Log in …
Content Taylor and Francis Online homepage Taylor and Francis Online homepage Log in …
Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers
M Poletto, C Di Loreto, D Marasco, E Poletto… - Biochemical and …, 2012 - Elsevier
Protein acetylation plays many roles within living cells, modulating metabolism, signaling
and cell response to environmental stimuli, as well as having an impact on pathological …
and cell response to environmental stimuli, as well as having an impact on pathological …
The fellowship of the RING: BRCA1, its partner BARD1 and their liaison in DNA repair and cancer
The breast cancer type 1 susceptibility protein (BRCA1) and its partner–the BRCA1-
associated RING domain protein 1 (BARD1)–are key players in a plethora of fundamental …
associated RING domain protein 1 (BARD1)–are key players in a plethora of fundamental …
[HTML][HTML] Modulation of BRCA1 mediated DNA damage repair by deregulated ER-α signaling in breast cancers
BRCA1 mutation carriers have a greater risk of developing cancers in hormone-responsive
tissues like breasts and ovaries. However, this tissue-specific incidence of BRCA1 related …
tissues like breasts and ovaries. However, this tissue-specific incidence of BRCA1 related …
Regulation of DNA repair in the absence of classical non-homologous end joining
YJ Kang, CT Yan - DNA repair, 2018 - Elsevier
Classical non-homologous end-joining (cNHEJ) is the main pathway for the repair of DNA
double strand breaks (DSBs) in mammalian cells. In the absence of c-NHEJ, an alternative …
double strand breaks (DSBs) in mammalian cells. In the absence of c-NHEJ, an alternative …
Relationship between MUTYH, OGG1 and BRCA1 mutations and mRNA expression in breast and ovarian cancer predisposition
C Moscatello, MD Nicola, S Veschi… - Molecular and …, 2021 - spandidos-publications.com
The aetiology of breast and ovarian cancer (BC/OC) is multi-factorial. At present, the
involvement of base excision repair (BER) glycosylases (MUTYH and OGG1) in BC/OC …
involvement of base excision repair (BER) glycosylases (MUTYH and OGG1) in BC/OC …