Prolyl oligopeptidase and its role in the organism: Attention to the most promising and clinically relevant inhibitors
K Babkova, J Korabecny, O Soukup… - Future medicinal …, 2017 - Taylor & Francis
Prolyl oligopeptidase (POP), also called prolyl endopeptidase, is a cytosolic enzyme
investigated by several research groups. It has been proposed to play an important role in …
investigated by several research groups. It has been proposed to play an important role in …
Diabetes in Cushing disease
G Mazziotti, AM Formenti, S Frara, F Maffezzoni… - Current diabetes …, 2017 - Springer
Abstract Purpose of Review This review focuses on the pathophysiological and clinical
aspects of diabetes mellitus occurring in patients with Cushing disease (CD). Recent …
aspects of diabetes mellitus occurring in patients with Cushing disease (CD). Recent …
Prescribing trends of antidiabetes medications in patients with type 2 diabetes and diabetic kidney disease: a cohort study
ST Harris, E Patorno, M Zhuo, SC Kim… - Diabetes Care, 2021 - Am Diabetes Assoc
OBJECTIVE To assess changes in antidiabetes medication class prescriptions over time
among patients with diabetic kidney disease (DKD), characteristics of patients prescribed …
among patients with diabetic kidney disease (DKD), characteristics of patients prescribed …
[HTML][HTML] Dose-dependent relationship between metformin and colorectal cancer occurrence among patients with Type 2 Diabetes—A nationwide cohort study
YT Chang, HL Tsai, YT Kung, YS Yeh, CW Huang… - Translational …, 2018 - Elsevier
BACKGROUND: Increasing bodies of evidence suggest that metformin may be beneficial in
the primary prevention of colorectal cancer (CRC), and a dose–response relationship has …
the primary prevention of colorectal cancer (CRC), and a dose–response relationship has …
The unique pharmacological and pharmacokinetic profile of teneligliptin: implications for clinical practice
A Ceriello, V De Nigris, H Iijima, T Matsui, M Gouda - Drugs, 2019 - Springer
Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that was approved for the
treatment of type 2 diabetes mellitus (T2DM) in Japan and Korea and is being researched in …
treatment of type 2 diabetes mellitus (T2DM) in Japan and Korea and is being researched in …
Changing Patterns of Antihyperglycaemic Treatment among Patients with Type 2 Diabetes in Hungary between 2015 and 2020—Nationwide Data from a Register …
G Jermendy, Z Kiss, G Rokszin, Z Abonyi-Tóth… - Medicina, 2022 - mdpi.com
Background and objectives: In the last couple of years, pharmacological management of
patients with type 2 diabetes mellitus (T2DM) have been markedly renewed. The aim of this …
patients with type 2 diabetes mellitus (T2DM) have been markedly renewed. The aim of this …
Cardiovascular safety of vildagliptin in patients with type 2 diabetes: a European multi‐database, non‐interventional post‐authorization safety study
R Williams, F de Vries, W Kothny… - Diabetes, Obesity …, 2017 - Wiley Online Library
The aim of this non‐interventional, multi‐database, analytical cohort study was to assess the
cardiovascular (CV) safety of vildagliptin vs other non‐insulin antidiabetic drugs (NIADs) …
cardiovascular (CV) safety of vildagliptin vs other non‐insulin antidiabetic drugs (NIADs) …
Small molecule inhibition of dipeptidyl peptidase-4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds
In diabetes, stromal cell-derived factor-1 (SDF-1) expression and progenitor cell recruitment
are reduced. Dipeptidyl peptidase-4 (DPP-4) inhibits SDF-1 expression and progenitor cell …
are reduced. Dipeptidyl peptidase-4 (DPP-4) inhibits SDF-1 expression and progenitor cell …
Use of Bacillus amyloliquefaciens HZ-12 for High-Level Production of the Blood Glucose Lowering Compound, 1-Deoxynojirimycin (DNJ), and Nutraceutical Enriched …
D Cai, M Liu, X Wei, X Li, Q Wang, CT Nomura… - Applied biochemistry …, 2017 - Springer
Deoxynojirimycin (DNJ) is an efficient α-glucosidase inhibitor (α-GI) with potential
applications in the prevention and treatment of diabetes. In this study, 16 Bacillus strains …
applications in the prevention and treatment of diabetes. In this study, 16 Bacillus strains …
The impact of metformin on survival in diabetes patients with operable colorectal cancer: A nationwide retrospective cohort study
PT Chu, TJ Chuang, SH Huang… - Journal of …, 2023 - journals.sagepub.com
Objective To investigate the impact of metformin on survival of diabetic patients following
surgery for colorectal cancer (CRC). Methods This was a retrospective cohort study. From …
surgery for colorectal cancer (CRC). Methods This was a retrospective cohort study. From …