Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale
An understanding of human brain individuality requires the integration of data on brain
organization across people and brain regions, molecular and systems scales, as well as …
organization across people and brain regions, molecular and systems scales, as well as …
Shared genetic architecture between Parkinson's disease and brain structural phenotypes
D Ma, S Li, J Shi, Y Liang, Z Hu, X Hao, M Li… - Movement …, 2023 - Wiley Online Library
Abstract Background Patients with Parkinson's disease (PD) have consistently demonstrated
brain structure abnormalities, indicating the presence of shared etiological and pathological …
brain structure abnormalities, indicating the presence of shared etiological and pathological …
Subcortical imaging-derived phenotypes are associated with the risk of Parkinson's disease: A Mendelian Randomization Study
Z Chen, J Liu, Y You - medRxiv, 2024 - medrxiv.org
Background The abnormalities of subcortical structures, such as putamen and caudate, play
a key role in the occurrence of Parkinson's disease (PD); however, whether and how …
a key role in the occurrence of Parkinson's disease (PD); however, whether and how …
Investigating the genetic relationship of intracranial and subcortical brain volumes with depression and other psychiatric disorders
Depression is one of the most common mental health disorders worldwide, yet its
neurobiological mechanisms remain poorly understood. Structural brain differences in …
neurobiological mechanisms remain poorly understood. Structural brain differences in …
Genetically regulated gene expression underlies the regional individuality of human brain organization and disease
An understanding of human brain individuality requires the integration of data on brain
organization across individuals, molecular and systems scales, as well as healthy and …
organization across individuals, molecular and systems scales, as well as healthy and …
[PDF][PDF] GENETICALLY REGULATED GENE EXPRESSION UNDERLIES THE REGIONAL INDIVIDUALITY OF HUMAN BRAIN ORGANIZATION AND DISEASE
N Hoang, N Sardaripour, G Ramey, K Schilling… - researchgate.net
An understanding of human brain individuality requires the integration of data on brain
organization across individuals, molecular and systems scales, as well as healthy and …
organization across individuals, molecular and systems scales, as well as healthy and …
Genetic architecture of brain morphology and overlap with neuropsychiatric traits
Uncovering the genetic architectures of brain morphology offers valuable insights into brain
development and disease. Genetic association studies of brain morphological phenotypes …
development and disease. Genetic association studies of brain morphological phenotypes …