Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

MS/MS-based molecular networking strain prioritization led to the discovery of a group of
cyclic depsipeptides from an endolichenic Xylaria sp. The main component, xylaroamide A …

Violaceotides B–E (1–4), four new cyclic tetrapeptides, along with seven known compounds,
were identified from the sponge-associated Aspergillus insulicola IMB18-072 co-cultivated …

Lanthipeptides are polycyclic peptides characterized by the presence of lanthionine (Lan)
and/or methyllanthionine (MeLan). They are members of the ribosomally synthesized and …

Metabolomics strives to capture the entirety of the metabolites in a biological system by
comprehensive analysis, often by liquid chromatography hyphenated to mass spectrometry …

In this study, two new cyclic lipopeptides (CLPs) pseudophomins C (3) and D (4) and two
known CLPs pseudophomins A (1) and B (2) were produced and characterized from the …

Historically, small molecules biosynthesised by bacteria have been an excellent source for
antibacterial drugs. Today, however, the rediscovery of known compounds is a significant …

Cyclopeptides are considered as one of the most important classes of compounds derived
from marine sources, due to their structural diversity and a myriad of their biological and …

This study represents a systematic chemical and biological study of the rufomycin (RUF)
class of cyclic heptapeptides, which our anti-TB drug discovery efforts have identified as …

A bioassay-guided chemical investigation of a bacterium, Streptomyces sp. CMB-MRB032,
isolated from sheep feces collected near Bathurst, Victoria, Australia, yielded the known …