The neutrophil

GL Burn, A Foti, G Marsman, DF Patel, A Zychlinsky - Immunity, 2021 - cell.com
Neutrophils are immune cells with unusual biological features that furnish potent
antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and …

Significance of LL‐37 on immunomodulation and disease outcome

B Yang, D Good, T Mosaiab, W Liu, G Ni… - BioMed Research …, 2020 - Wiley Online Library
LL‐37, also called cathelicidin, is an important part of the human immune system, which can
resist various pathogens. A plethora of experiments have demonstrated that it has the …

[HTML][HTML] Translocated microbiome composition determines immunological outcome in treated HIV infection

K Nganou-Makamdop, A Talla, AA Sharma, S Darko… - Cell, 2021 - cell.com
The impact of the microbiome on HIV disease is widely acknowledged although the
mechanisms downstream of fluctuations in microbial composition remain speculative. We …

Interactions of HIV and antiretroviral therapy with neutrophils and platelets

M Madzime, TM Rossouw, AJ Theron… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are important components of the innate immune system that mediate pathogen
defense by multiple processes including phagocytosis, release of proteolytic enzymes …

Neutrophils as a potential therapeutic target in Alzheimer's disease

ML Aries, T Hensley-McBain - Frontiers in Immunology, 2023 - frontiersin.org
Alzheimer's disease (AD) is the leading cause of dementia in the United States. Sporadic or
late-onset AD remains incompletely understood, with age as the current greatest risk factor …

Impact of the Microbiome on the Immune System

CB Lambring, S Siraj, K Patel… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Higher organisms are all born with general immunity as well as with, increasingly, more
specific immune systems. All immune mechanisms function with the intent of aiding the body …

Role of the human vaginal microbiota in the regulation of inflammation and sexually transmitted infection acquisition: Contribution of the non-human primate model to …

C Adapen, L Réot, E Menu - Frontiers in Reproductive Health, 2022 - frontiersin.org
The human vaginal microbiota has a central role in the regulation of the female reproductive
tract (FRT) inflammation. Indeed, on one hand an optimal environment leading to a …

The altered metabolites contributed by dysbiosis of gut microbiota are associated with microbial translocation and immune activation during HIV infection

Y Zhang, Z Xie, J Zhou, Y Li, C Ning, Q Su… - Frontiers in …, 2023 - frontiersin.org
Background The immune activation caused by microbial translocation has been considered
to be a major driver of HIV infection progression. The dysbiosis of gut microbiota has been …

Gut microbiome changes associated with HIV infection and sexual orientation

J Zhou, Y Zhang, P Cui, L Luo, H Chen… - Frontiers in Cellular …, 2020 - frontiersin.org
Background: Many studies have explored changes in the gut microbiome associated with
HIV infection, but the consistent pattern of changes has not been clarified. Men who have …

Differential signature of the microbiome and neutrophils in the oral cavity of HIV-infected individuals

E Perez Rosero, S Heron, J Jovel, CR O'Neil… - Frontiers in …, 2021 - frontiersin.org
HIV infection is associated with a wide range of changes in microbial communities and
immune cell components of the oral cavity. The purpose of this study was to evaluate the …