Myometrial physiology–time to translate?

S Arrowsmith, A Kendrick, JA Hanley… - Experimental …, 2014 - Wiley Online Library
New Findings What is the topic of this review? To provide an overview of the current
understanding of myometrial contractility and give examples of where this has or is close to …

Roles and regulation of the matrix metalloproteinase system in parturition

J Geng, C Huang, S Jiang - Molecular reproduction and …, 2016 - Wiley Online Library
Significant tissue destruction, repair, and remodeling are involved in parturition, which
involves fetal membrane rupture, cervical ripening, and uterine contraction and its …

Diabetes is associated with impairment of uterine contractility and high Caesarean section rate

S Al-Qahtani, A Heath, S Quenby, F Dawood, R Floyd… - Diabetologia, 2012 - Springer
Aims/hypothesis The prevalence of births worldwide complicated by diabetes mellitus is
increasing. In the UK, for example,< 25% of diabetic women have a non-instrumental …

Pharmacological techniques for the in vitro study of the uterus

DJ Crankshaw - Journal of pharmacological and toxicological methods, 2001 - Elsevier
During the first decade of the 21st century it is unlikely that the pages of specialist
pharmacology journals will overflow with papers reporting studies on the isolated uterus …

High glucose induced HIF-1α/TREK1 expression and myometrium relaxation during pregnancy

T Li, J Fei, H Yu, X Wang, J Bai, F Chen, D Li… - Frontiers in …, 2023 - frontiersin.org
Background The incidence of gestational diabetes mellitus (GDM) is increasing worldwide.
GDM patients have a significantly higher rate of cesarean section and postpartum …

Effects of long‐term diabetes on the structure and cell proliferation of the myometrium in the early pregnancy of mice

RR Favaro, RM Salgado, PR Raspantini… - International Journal …, 2010 - Wiley Online Library
It is known that the development of diabetic complications in human pregnancy is directly
related to the severity and the duration of this pathology. In this study, we developed a model …

Maternal phenotype: how do age, obesity and diabetes affect myometrial function?

C Prendergast - Current Opinion in Physiology, 2020 - Elsevier
The prevalence of obesity and diabetes has increased rapidly in the general population over
the last few decades, meaning that a significant number of women of reproductive age are …

Influence of high glucose in the expression of miRNAs and IGF1R signaling pathway in human myometrial explants

RR Favaro, DM Morales-Prieto, J Herrmann… - Archives of Gynecology …, 2021 - Springer
Purpose Several roles are attributed to the myometrium including sperm and embryo
transport, menstrual discharge, control of uterine blood flow, and labor. Although being a …

[PDF][PDF] Clarithromycin inhibits myometrial contractions in isolated human myometrium independent of stimulus

H Celik, A Ayar - Physiological research, 2002 - biomed.cas.cz
Erythromycin has a well-known dual effect on the contractility of the gastrointestinal system
and recently has also been shown to inhibit contractions of the rat myometrium. The aim of …

The endothelin-converting enzyme-1/endothelin-1 pathway plays a critical role in inflammation-associated premature delivery in a mouse model

W Wang, H Yen, CH Chen, R Soni, N Jasani… - The American journal of …, 2008 - Elsevier
Premature delivery occurs in 12% of all births and accounts for nearly half of long-term
morbidity. Current therapeutic approaches to preterm delivery are ineffective and present …