[HTML][HTML] Artificial intelligence-driven morphology-based enrichment of malignant cells from body fluid
A Mavropoulos, C Johnson, V Lu, J Nieto… - Modern Pathology, 2023 - Elsevier
Cell morphology is a fundamental feature used to evaluate patient specimens in pathologic
analysis. However, traditional cytopathology analysis of patient effusion samples is limited …
analysis. However, traditional cytopathology analysis of patient effusion samples is limited …
FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer
While oncogenes promote cancer cell growth, unrestrained proliferation represents a
significant stressor to cellular homeostasis networks such as the DNA damage response …
significant stressor to cellular homeostasis networks such as the DNA damage response …
Isolation and characterization of two newly established thymoma PDXs from two relapses of the same patient: a new tool to investigate thymic malignancies
P Mendogni, R Affatato, E Cabri, M Chiappa… - Journal of Experimental …, 2022 - Springer
Background Thymic malignancies are a heterogeneous group of rare cancers for which
systemic chemotherapy is the standard treatment in the setting of advanced, recurrent or …
systemic chemotherapy is the standard treatment in the setting of advanced, recurrent or …
FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer
The genetic principle of synthetic lethality is clinically validated in cancers with loss of
specific DNA damage response (DDR) pathway genes (ie BRCA1/2 tumor suppressor …
specific DNA damage response (DDR) pathway genes (ie BRCA1/2 tumor suppressor …
Reduced frequency of clonal hematopoiesis in Parkinson's disease
To test if clonal hematopoiesis of indeterminate potential (CHIP) is associated with the
incidence of Parkinson's Disease (PD), we analyzed blood whole exome sequencing data …
incidence of Parkinson's Disease (PD), we analyzed blood whole exome sequencing data …