Improvement of the sensitivity of lateral flow systems for detecting mycotoxins: Up‐to‐date strategies and future perspectives
Z Li, A Jallow, S Nidiaye, Y Huang… - … Reviews in Food …, 2024 - Wiley Online Library
Mycotoxins are dangerous human and animal health‐threatening secondary fungal
metabolites that can be found in various food and agricultural products. Several countries …
metabolites that can be found in various food and agricultural products. Several countries …
[HTML][HTML] Structural Insights into Protein–Aptamer Recognitions Emerged from Experimental and Computational Studies
Aptamers are synthetic nucleic acids that are developed to target with high affinity and
specificity chemical entities ranging from single ions to macromolecules and present a wide …
specificity chemical entities ranging from single ions to macromolecules and present a wide …
Amplification-free ratiometric electrochemical aptasensor for point-of-care detection of therapeutic monoclonal antibodies
J Wan, Y Liang, Q Hu, Z Liang, W Feng, Y Tian… - Analytical …, 2023 - ACS Publications
The rapid quantification of therapeutic monoclonal antibodies (mAbs) is of great significance
to their pharmacokinetics/pharmacodynamics (PK/PD) research and the personalized …
to their pharmacokinetics/pharmacodynamics (PK/PD) research and the personalized …
A novel ratiometric electrochemical aptasensor based on M-shaped functional DNA complexes for simultaneous detection of trace lead and mercury ions in series …
X Wang, M Xu, Y Kuang, X Liu, J Yuan - Journal of Hazardous Materials, 2024 - Elsevier
Simultaneous quantification of multiple heavy metal ions (HMIs) is essential due to
enhanced toxicity induced by synergistic effects. The currently available detection methods …
enhanced toxicity induced by synergistic effects. The currently available detection methods …
Rapid isolation of anti-idiotype aptamers for quantification of human monoclonal antibodies against SARS-CoV-2 spike protein
Therapeutic antibodies that block viral entry have already proven to be important, first line
drugs for treatments of viral infections. In the case of SARS-CoV-2, combinations of multiple …
drugs for treatments of viral infections. In the case of SARS-CoV-2, combinations of multiple …
One-step high-throughput detection of low-abundance biomarker BDNF using a biolayer interferometry-based 3D aptasensor
S Gao, Q Li, S Zhang, X Sun, X Zheng, H Qian… - Biosensors and …, 2022 - Elsevier
Although biosensors for signal monitoring have been extensively developed, their
application in one-step high-throughput detection of low-abundance disease biomarkers …
application in one-step high-throughput detection of low-abundance disease biomarkers …
Structure-based investigation of a DNA aptamer targeting PTK7 reveals an intricate 3D fold guiding functional optimization
A He, L Wan, Y Zhang, Z Yan, P Guo, D Han… - Proceedings of the …, 2024 - pnas.org
DNA aptamers have emerged as novel molecular tools in disease theranostics owing to
their high binding affinity and specificity for protein targets, which rely on their ability to fold …
their high binding affinity and specificity for protein targets, which rely on their ability to fold …
[HTML][HTML] Development of an anti-idiotype aptamer-based electrochemical sensor for a humanized therapeutic antibody monitoring
Therapeutic monoclonal antibodies (mAbs) are currently the most effective medicines for a
wide range of diseases. Therefore, it is expected that easy and rapid measurement of mAbs …
wide range of diseases. Therefore, it is expected that easy and rapid measurement of mAbs …
[HTML][HTML] Monoclonal antibodies (mAbs) optical detection by coupling innovative imprinted biopolymers and magnetic beads: The case of therapeutic mAb anti …
F Torrini, F Battaglia, D Sestaioni, P Palladino… - Sensors and Actuators B …, 2023 - Elsevier
Immunotherapy has revolutionized modern medicine, becoming the largest part of the
growing bio-drugs market. Along with the progress in this direction, the need for reliable …
growing bio-drugs market. Along with the progress in this direction, the need for reliable …
Site-Directed Electrochemical Grafting for Amplified Detection of Antibody Pharmaceuticals
J Wan, Y Tian, D Wu, Z Ye, S Chen, Q Hu… - Analytical …, 2024 - ACS Publications
Antibody pharmaceuticals have become the most popular immunotherapeutic drugs and are
often administered with low serum drug dosages. Hence, the development of a highly …
often administered with low serum drug dosages. Hence, the development of a highly …