Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?
CL Kuo, A Ponneri Babuharisankar, YC Lin… - Journal of biomedical …, 2022 - Springer
The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …
Paclitaxel's mechanistic and clinical effects on breast cancer
Paclitaxel (PTX), the most widely used anticancer drug, is applied for the treatment of
various types of malignant diseases. Mechanisms of PTX action represent several ways in …
various types of malignant diseases. Mechanisms of PTX action represent several ways in …
[HTML][HTML] Biological effects and medical applications of infrared radiation
SR Tsai, MR Hamblin - Journal of Photochemistry and Photobiology B …, 2017 - Elsevier
Infrared (IR) radiation is electromagnetic radiation with wavelengths between 760 nm and
100,000 nm. Low-level light therapy (LLLT) or photobiomodulation (PBM) therapy generally …
100,000 nm. Low-level light therapy (LLLT) or photobiomodulation (PBM) therapy generally …
The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology
P Bernardi, A Rasola, M Forte… - Physiological …, 2015 - journals.physiology.org
The mitochondrial permeability transition (PT) is a permeability increase of the inner
mitochondrial membrane mediated by a channel, the permeability transition pore (PTP) …
mitochondrial membrane mediated by a channel, the permeability transition pore (PTP) …
Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection
MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …
oncology patients. However, these antineoplastic treatments may also induce adverse …
Oxidative stress in the tumor microenvironment and its relevance to cancer immunotherapy
NS Aboelella, C Brandle, T Kim, ZC Ding, G Zhou - Cancers, 2021 - mdpi.com
Simple Summary Cancer cells are consistently under oxidative stress, as reflected by
elevated basal level of reactive oxygen species (ROS), due to increased metabolism driven …
elevated basal level of reactive oxygen species (ROS), due to increased metabolism driven …
Chemopreventive effects of hesperidin against paclitaxel-induced hepatotoxicity and nephrotoxicity via amendment of Nrf2/HO-1 and caspase-3/Bax/Bcl-2 signaling …
Paclitaxel (PTX) is a widely used chemotherapeutic drug particularly effective against lung,
breast, and ovarian cancer, though its usefulness is limited due to its multi-organ toxicity …
breast, and ovarian cancer, though its usefulness is limited due to its multi-organ toxicity …
Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems
NP Staff, JC Fehrenbacher, M Caillaud, MI Damaj… - Experimental …, 2020 - Elsevier
Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …
[HTML][HTML] Emerging role of NRF2 in ROS-mediated tumor chemoresistance
D Xue, X Zhou, J Qiu - Biomedicine & pharmacotherapy, 2020 - Elsevier
Chemoresistance is a central cause for the tumor management failure. Cancer cells disrupt
the redox homeostasis through reactive oxygen species (ROS) regulatory mechanisms …
the redox homeostasis through reactive oxygen species (ROS) regulatory mechanisms …
Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy
Anti-cancer drugs such as vincristine, paclitaxel, oxaliplatin, cisplatin and bortezomib are
well reported to exert direct and indirect effects on sensory nerves to alter the amplitude of …
well reported to exert direct and indirect effects on sensory nerves to alter the amplitude of …