Although the term “asthma” has been applied to all patients with airway lability and variable
chest symptoms for centuries, phenotypes of asthma with distinct clinical and molecular …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

abstract Obesity is an important global health issue for both children and adults. Obesity
increases the prevalence and incidence of asthma and also increases the risk for severe …

Rationale: The role of obesity-associated insulin resistance (IR) in airflow limitation in
asthma is uncertain. Objectives: Using data in the Severe Asthma Research Program 3 …

Background and aims Scar tissue accumulation in organs is the underlying cause of many
fibrotic diseases. Due to the extensive array of organs affected, the long-term nature of …

Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

Diabetes mellitus is a chronic, progressive, incompletely understood metabolic disorder
whose prevalence has been increasing steadily worldwide. Even though little attention has …

The proportion of obese or overweight patients in COPD patients is increasing. Although
BMI, WC and other easy to measure indicators have been proven to be related to the risk of …

Non-communicable diseases, like diabetes, cardiovascular diseases, cancer, stroke, chronic
obstructive pulmonary disease, osteoporosis, arthritis, Alzheimer's disease and other more …

Population-based studies showing the negative impact of type 2 diabetes (T2D) on lung
function are overviewed. Among the well-recognized pathophysiological mechanisms, the …