A timeline of tumour-associated macrophage biology
L Cassetta, JW Pollard - Nature Reviews Cancer, 2023 - nature.com
Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …
populated by many immune cells, of which macrophages are among the most abundant …
[HTML][HTML] Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer
MB Buechler, W Fu, SJ Turley - Immunity, 2021 - cell.com
Fibroblasts and macrophages are present in all tissues, and mounting evidence supports
that these cells engage in direct communication to influence the overall tissue …
that these cells engage in direct communication to influence the overall tissue …
The M-CSF receptor in osteoclasts and beyond
SH Mun, PSU Park, KH Park-Min - Experimental & molecular medicine, 2020 - nature.com
Colony-stimulating factor 1 receptor (CSF1R, also known as c-FMS) is a receptor tyrosine
kinase. Macrophage colony-stimulating factor (M-CSF) and IL-34 are ligands of CSF1R …
kinase. Macrophage colony-stimulating factor (M-CSF) and IL-34 are ligands of CSF1R …
[HTML][HTML] Establishment and maintenance of the macrophage niche
M Guilliams, GR Thierry, J Bonnardel, M Bajenoff - Immunity, 2020 - cell.com
Self-maintaining resident macrophages populate all mammalian organs. In addition to their
role as immune sentinels, macrophages perform day-to-day functions essential to tissue …
role as immune sentinels, macrophages perform day-to-day functions essential to tissue …
CSF-1 receptor signaling in myeloid cells
ER Stanley, V Chitu - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
The CSF-1 receptor (CSF-1R) is activated by the homodimeric growth factors colony-
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …
Roles of tumor-associated macrophages in tumor progression: implications on therapeutic strategies
S Zhu, M Yi, Y Wu, B Dong, K Wu - Experimental Hematology & Oncology, 2021 - Springer
Macrophages are heterogeneous cells that present as different functional phenotypes due to
their plasticity. They can be classified into two categories, namely M1-and M2-like …
their plasticity. They can be classified into two categories, namely M1-and M2-like …
Emerging roles for CSF-1 receptor and its ligands in the nervous system
The colony-stimulating factor-1 receptor (CSF-1R) kinase regulates tissue macrophage
homeostasis, osteoclastogenesis, and Paneth cell development. However, recent studies in …
homeostasis, osteoclastogenesis, and Paneth cell development. However, recent studies in …
Glucose transporter 1 critically controls microglial activation through facilitating glycolysis
Background Uncontrolled microglial activation contributes to the pathogenesis of various
neurodegenerative diseases. Previous studies have shown that proinflammatory microglia …
neurodegenerative diseases. Previous studies have shown that proinflammatory microglia …
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
BE Clausen, C Burkhardt, W Reith, R Renkawitz… - Transgenic …, 1999 - Springer
Conditional mutagenesis in mice has recently been made possible through the combination
of gene targeting techniques and site–directed mutagenesis, using the bacteriophage P1 …
of gene targeting techniques and site–directed mutagenesis, using the bacteriophage P1 …
Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain
F Alliot, I Godin, B Pessac - Developmental Brain Research, 1999 - Elsevier
Microglia, the resident CNS macrophages, represent about 10% of the adult brain cell
population. Although described a long time ago, their origin and developmental lineage is …
population. Although described a long time ago, their origin and developmental lineage is …