[HTML][HTML] The gut virome: A new microbiome component in health and disease
Z Cao, N Sugimura, E Burgermeister, MP Ebert… - …, 2022 - thelancet.com
The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …
[HTML][HTML] Detection of viral infections by innate immunity
Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral
innate immune system as they detect conserved viral pathogen-associated molecular …
innate immune system as they detect conserved viral pathogen-associated molecular …
Early life microbial exposures and allergy risks: opportunities for prevention
H Renz, C Skevaki - Nature Reviews Immunology, 2021 - nature.com
Allergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence,
particularly in westernized countries. Although a detailed mechanistic explanation for this …
particularly in westernized countries. Although a detailed mechanistic explanation for this …
[HTML][HTML] The gut microbiota in the pathogenesis and therapeutics of inflammatory bowel disease
In the twenty first century, the changing epidemiology of inflammatory bowel disease (IBD)
globally with increasing disease incidence across many countries relates to the altered gut …
globally with increasing disease incidence across many countries relates to the altered gut …
[HTML][HTML] Toll-like receptors and inflammatory bowel disease
Y Lu, X Li, S Liu, Y Zhang, D Zhang - Frontiers in immunology, 2018 - frontiersin.org
Inflammatory bowel disease (IBD) is one relapsing and lifelong disease that affects millions
of patients worldwide. Increasing evidence has recently highlighted immune-system …
of patients worldwide. Increasing evidence has recently highlighted immune-system …
Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome
Objective Faecal microbiota transplantation (FMT) is effective for the treatment of recurrent
Clostridium difficile infection (CDI). Studies have shown bacterial colonisation after FMT, but …
Clostridium difficile infection (CDI). Studies have shown bacterial colonisation after FMT, but …
High frequency of intestinal TH17 cells correlates with microbiota alterations and disease activity in multiple sclerosis
I Cosorich, G Dalla-Costa, C Sorini, R Ferrarese… - Science …, 2017 - science.org
T helper 17 (TH17) cells are key players in multiple sclerosis (MS), and studies in animal
models demonstrated that effector TH17 cells that trigger brain autoimmunity originate in the …
models demonstrated that effector TH17 cells that trigger brain autoimmunity originate in the …
[HTML][HTML] Pathogenesis of inflammatory bowel disease and recent advances in biologic therapies
DH Kim, JH Cheon - Immune network, 2017 - synapse.koreamed.org
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …
[HTML][HTML] New insights into intestinal phages
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …
[HTML][HTML] Bacteriophages and the immune system
M Popescu, JD Van Belleghem… - Annual review of …, 2021 - annualreviews.org
Bacteriophages—viruses that infect bacteria—are abundant within our bodies, but their
significance to human health is only beginning to be explored. Here, we synthesize what is …
significance to human health is only beginning to be explored. Here, we synthesize what is …