The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early
repolarization syndrome (ERS), have captured the interest of the cardiology community over …

This international consensus statement is the collaborative effort of three medical societies
representing electrophysiology in North America, Europe and Asian-Pacific area: the Heart …

Background: Implicit in the genetic evaluation of patients with suspected genetic diseases is
the assumption that the genes evaluated are causative for the disease based on robust …

In children with structurally normal hearts, the mechanisms of arrhythmias are usually the
same as in the adult patient. Some arrhythmias are particularly associated with young age …

Sudden cardiac death occurs in a broad spectrum of cardiac pathologies and is an important
cause of mortality in the general population. Genetic studies conducted during the past 20 …

A cardiac arrhythmia simply defined is a variation from the normal heart rate and/or rhythm
that is not physiologically justified. Recent years have witnessed important advances in our …

KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

Optimal cardiac function depends on proper timing of excitation and contraction in various
regions of the heart, as well as on appropriate heart rate. This is accomplished via …

BACKGROUND: L-type calcium channel (LTCC) mutations have been associated with
Brugada syndrome (BrS), short QT (SQT) syndrome, and Timothy syndrome (LQT8). Little is …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …