Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation

M Matsuoka, KT Jeang - Nature Reviews Cancer, 2007 - nature.com
It has been 30 years since a'new'leukaemia termed adult T-cell leukaemia (ATL) was
described in Japan, and more than 25 years since the isolation of the retrovirus, human T …

Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity

I Azran, Y Schavinsky-Khrapunsky, M Aboud - Retrovirology, 2004 - Springer
HTLV-1 is the etiological agent of adult T-cell leukemia (ATL), the neurological syndrome
TSP/HAM and certain other clinical disorders. The viral Tax protein is considered to play a …

Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1

J Arnold, B Yamamoto, M Li, AJ Phipps, I Younis… - Blood, 2006 - ashpublications.org
Natural antisense viral transcripts have been recognized in retroviruses, including human T-
cell leukemia virus type 1 (HTLV-1), HIV-1, and feline immunodeficiency virus (FIV), and …

Human T lymphotropic virus type 1 (HTLV-1): molecular biology and oncogenesis

P Kannian, PL Green - Viruses, 2010 - mdpi.com
Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

Transcriptional Control of Spliced and Unspliced Human T-Cell Leukemia Virus Type 1 bZIP Factor (HBZ) Gene

M Yoshida, Y Satou, J Yasunaga, J Fujisawa… - Journal of …, 2008 - Am Soc Microbiol
The human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper factor (HBZ) gene is
encoded by the minus strand of the HTLV-1 provirus and transcribed from the 3′ long …

Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits

VW Valeri, A Hryniewicz, V Andresen… - Blood, The Journal …, 2010 - ashpublications.org
The identification of the genes necessary for human T-cell leukemia virus (HTLV-1)
persistence in humans may provide targets for therapeutic approaches. We demonstrate that …

Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions

C Nicot, RL Harrod, V Ciminale, G Franchini - Oncogene, 2005 - nature.com
The human T-cell leukemia/lymphoma virus (HTLV) genome, in addition to the structural
Gag and Env proteins and retroviral enzymes, carries a region at its 3′ end originally …

Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance …

C Grant, K Barmak, T Alefantis, J Yao… - Journal of cellular …, 2002 - Wiley Online Library
Human T cell lymphotropic/leukemia virus type I (HTLV‐I) has been identified as the
causative agent of both adult T cell leukemia (ATL) and HTLV‐I‐associated …

HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties

V Ciminale, F Rende, U Bertazzoni… - Frontiers in …, 2014 - frontiersin.org
HTLV-1 and HTLV-2 share broad similarities in their overall genetic organization and
expression pattern, but they differ substantially in their pathogenic properties. This review …

Mechanisms of human T-lymphotropic virus type 1 transmission and disease

MD Lairmore, R Haines, R Anupam - Current opinion in virology, 2012 - Elsevier
Human T-lymphotrophic virus type-1 (HTLV-1) infects approximately 15–20 million people
worldwide, with endemic areas in Japan, the Caribbean, and Africa. The virus is spread …