Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

The optimal level of immunosuppression in solid organ transplantation, in particular for the
liver, is a delicate balance between the benefit of preventing rejection and the adverse side …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

BACKGROUND & AIMS: The aim of this study was to generate an improved prognostic
model for predicting recurrence in liver transplant candidates with hepatocellular carcinoma …

The selection of liver transplantation (LT) candidates with hepatocellular carcinoma (HCC) is
currently validated based on Milan criteria. The use of extended criteria has remained a …

Background & Aims The AFP model was shown to be superior to the Milan criteria for
predicting hepatocellular carcinoma (HCC) recurrence after liver transplantation in a French …

Surgery for the removal of a primary tumor presents an opportunity to eradicate cancer or
arrest its progression, but is also believed to promote the outbreak of pre-existing …

Surgery is a crucial intervention in most cancer patients, but the perioperative period is
characterized by increased risks for future outbreak of preexisting micrometastases and the …

Liver transplantation is the best treatment of patients with unresectable early hepatocellular
carcinoma, allowing disease-free survival rates of 60–80% at 5 years. Despite these good …

Background Liver transplantation (LT) offers a possible cure for carefully selected patients
with hepatocellular carcinoma (HCC). Studies report that preoperative alpha‐fetoprotein …