The iterative threading assembly refinement (I-TASSER) server is an integrated platform for
automated protein structure and function prediction based on the sequence-to-structure-to …

Protein structure prediction from amino acid sequence has been one of the most challenging
aspects in computational structural biology despite significant progress in recent years …

SWISS‐MODEL pioneered the field of automated modeling as the first protein modeling
service on the Internet. In combination with the visualization tool Swiss‐PdbViewer, the …

A key challenge of the post-genomic era is the identification of the function (s) of all the
molecules in a given organism. Here, we review the status of sequence and structure-based …

Automated protein structure prediction is becoming a mainstream tool for biological
research. This has been fueled by steady improvements of publicly available automated …

Motivation: In recent years, development of a single-method fold-recognition server lags
behind consensus and multiple template techniques. However, a good consensus …

We introduce PULCHRA, a fast and robust method for the reconstruction of full‐atom protein
models starting from a reduced protein representation. The algorithm is particularly suitable …

The community-wide GPCR Dock assessment is conducted to evaluate the status of
molecular modeling and ligand docking for human G protein-coupled receptors. The present …

The protein universe is the set of all proteins of all organisms. Here, all currently known
sequences are analyzed in terms of families that have single-domain or multidomain …

Motivation: Generation of structural models and recognition of homologous relationships for
unannotated protein sequences are fundamental problems in bioinformatics. Improving the …