Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …

Traumatic brain injury (TBI) is a pervasive problem worldwide for which no effective
treatment is currently available. Although most studies have focused on the pathology of the …

Objective To assess the effect of serine protein inhibitor A3N (serpinA3N) in ischemic stroke
and to explore its mechanism of action. Methods Mouse ischemic stroke model was induced …

In the central nervous system, nitric oxide (NO), a free gas with multitudinous bioactivities, is
mainly produced from the oxidation of L-arginine by neuronal nitric oxide synthase (nNOS) …

The complex between the N-methyl-d-aspartate receptor (NMDAR), neuronal nitric oxide
synthase (nNOS), and the postsynaptic density protein-95 (PSD-95) is an attractive …

Glutamate N-methyl-D-aspartate receptor (NMDAR) is critical for promoting physiological
synaptic plasticity and neuronal viability. As a major subpopulation of the NMDAR, the …

Introduction The relationship between oscillatory activity in hippocampus and cognitive
impairment in traumatic brain injury (TBI) remains unclear. Although TBI decreases gamma …

Our previous study indicates that Silent information regulator 1 (Sirt1) is involved in
macroautophagy by upregulating light chain 3 (LC3) expression in astrocyte to exert a …

Rationale Current pharmacological approaches to treatment of post-traumatic stress
disorder (PTSD) lack adequate effectiveness. As a result, identifying new molecular targets …