The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …

In the past decades our knowledge about fungal cell wall architecture increased
tremendously and led to the identification of many enzymes involved in polysaccharide …

The Orm family proteins are conserved integral membrane proteins of the endoplasmic
reticulum that are key homeostatic regulators of sphingolipid biosynthesis. Orm proteins bind …

Studies of the processes leading to the construction of a bud and its separation from the
mother cell in Saccharomyces cerevisiae have provided foundational paradigms for the …

Productive cell proliferation involves efficient and accurate splitting of the dividing cell into
two separate entities. This orderly process reflects coordination of diverse cytological events …

The target of rapamycin (TOR) signalling pathway plays a key role in the coordination
between cellular growth and the cell cycle machinery in eukaryotes. The underlying …

Temporal control over protein phosphorylation and dephosphorylation is crucial for accurate
chromosome segregation and for completion of the cell division cycle during exit from …

Cell division is a fundamental but complex process that gives rise to two daughter cells. It
includes an ordered set of events, altogether called “the cell cycle”, that culminate with …

Cytokinesis is essential for cell proliferation in all domains of life. Because the core
components and mechanisms of cytokinesis are conserved from fungi to humans, the …

Over the past decade Hippo kinase signalling has been established as an essential tumour
suppressor pathway controlling tissue growth in flies and mammals. All members of the …