Computational models in cardiology
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …
the challenging field of virtual design and testing of technologies in a patient-specific …
The 'Digital Twin'to enable the vision of precision cardiology
J Corral-Acero, F Margara, M Marciniak… - European heart …, 2020 - academic.oup.com
Providing therapies tailored to each patient is the vision of precision medicine, enabled by
the increasing ability to capture extensive data about individual patients. In this position …
the increasing ability to capture extensive data about individual patients. In this position …
The openCARP simulation environment for cardiac electrophysiology
Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …
long and rich tradition of computational modeling. Nevertheless, no community standard for …
[HTML][HTML] A framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs
Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …
[HTML][HTML] Electro-mechanical whole-heart digital twins: a fully coupled multi-physics approach
T Gerach, S Schuler, J Fröhlich, L Lindner… - Mathematics, 2021 - mdpi.com
Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …
medicine and support clinical decision making by providing a powerful tool to understand …
[HTML][HTML] Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model
Anatomically accurate and biophysically detailed bidomain models of the human heart have
proven a powerful tool for gaining quantitative insight into the links between electrical …
proven a powerful tool for gaining quantitative insight into the links between electrical …
[HTML][HTML] 3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
Linking statistical shape models and simulated function in the healthy adult human heart
Cardiac anatomy plays a crucial role in determining cardiac function. However, there is a
poor understanding of how specific and localised anatomical changes affect different …
poor understanding of how specific and localised anatomical changes affect different …
A rule‐based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts
R Doste, D Soto‐Iglesias, G Bernardino… - … journal for numerical …, 2019 - Wiley Online Library
Rule‐based methods are often used for assigning fiber orientation to cardiac anatomical
models. However, existing methods have been developed using data mostly from the left …
models. However, existing methods have been developed using data mostly from the left …