Low back pain (LBP) is a major reason for disability, and symptomatic intervertebral disc
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …

Abstract Alzheimer's disease (AD), a common irreversible neurodegenerative disease
characterized by amyloid-β plaques, neurofibrillary tangles, and changes in tau …

Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a natural phenol that is present in
the skin of the grape, blueberry, raspberry, mulberry, and peanut. This substance is …

Intervertebral disc degenerative disease (IDD), which usually causes lower back and neck
pain, is one of the most widespread musculoskeletal disorders and often causes a low …

Intervertebral disc degeneration (IDD) is a high incidence disease of musculoskeletal
system that often leads to stenosis, instability, pain and even deformity of the spinal …

Intervertebral disc (IVD) degeneration (IDD) is a common disorder that affects the spine and
is a major cause of lower back pain (LBP). The extracellular matrix (ECM) is the structural …

To investigate whether TP53‐induced glycolysis and apoptosis regulator (TIGAR)
participates in compression‐induced intervertebral disc (IVD) degeneration, and to …

Intervertebral disc degeneration (IVDD) is a main contributor to low back and radicular pain,
which imposes heavy economic burdens on society. However, the etiology and mechanism …

In living organisms, cells sense mechanical forces (shearing, tensile, and compressive) and
respond to those physical cues through a process called mechanotransduction. This …

Intervertebral disc degeneration (IVDD) is commonly associated with many spinal problems,
such as low back pain, and significantly impacts a patient's quality of life. However, current …