Peptidomimetic therapeutics: scientific approaches and opportunities

N Qvit, SJS Rubin, TJ Urban, D Mochly-Rosen… - Drug discovery today, 2017 - Elsevier
Highlights•Naturally occurring peptides are important resources in order to develop
pharmaceutical lead compounds.•Natural peptides are often limited by poor stability or …

Curses or cures: A review of the numerous benefits versus the biosecurity concerns of conotoxin research

WE Bjørn-Yoshimoto, IBL Ramiro, M Yandell… - Biomedicines, 2020 - mdpi.com
Conotoxins form a diverse group of peptide toxins found in the venom of predatory marine
cone snails. Decades of conotoxin research have provided numerous measurable scientific …

[HTML][HTML] Anti‐GPVI nanobody blocks collagen‐and atherosclerotic plaque–induced GPVI clustering, signaling, and thrombus formation

NJ Jooss, CW Smith, A Slater, SJ Montague… - Journal of Thrombosis …, 2022 - Elsevier
Background The collagen receptor glycoprotein VI (GPVI) is an attractive antiplatelet target
due to its critical role in thrombosis but minor involvement in hemostasis. Objective To …

The use of eptifibatide for suspected pump thrombus or thrombosis in patients with left ventricular assist devices

BR Tellor, JR Smith, SM Prasad, SM Joseph… - The Journal of Heart and …, 2014 - Elsevier
Background Pump thrombosis in patients with left ventricular assist devices (LVADs)
continues to present treatment challenges. Anti-coagulation strategies used to treat this …

Penyakit kardiovaskular: Seri pengobatan rasional

A Willyono, B Presley, C Kamallan, D Primayani… - 2018 - repository.ubaya.ac.id
Buku Penyakit Kardiovaskular ini membahas secara holistik dari sudut pandang ahli, yaitu
dokter, apoteker dan farmasi klinis. Buku ini membahas beberapa penyakit kardiovaskular …

Efficacy and safety of eptifibatide versus tirofiban in acute coronary syndrome patients: a systematic review and meta‐analysis

X Zhou, X Wu, H Sun, J Li - Journal of Evidence‐Based …, 2017 - Wiley Online Library
Abstract Background Glycoprotein IIb/IIIa inhibitors were the strongest available antiplatelet
therapy and have been shown to reduce cardiac ischemic complications in patients …

Management of a decompensated acute-on-chronic intracranial venous sinus thrombosis

C Serna Candel, V Hellstern, T Beitlich… - Therapeutic …, 2019 - journals.sagepub.com
A 34-year-old female patient presented during the 10th week of her second gravidity with
headache, nausea and vomiting 2 weeks before admission. Her medical history was …

[HTML][HTML] Editorial of Special Column “Novel Peptides and Peptidomimetics in Drug Discovery”

J Cai, L Wei - Acta Pharmaceutica Sinica. B, 2021 - ncbi.nlm.nih.gov
Since insulin, a natural peptide composed of 51 amino acids, was first isolated and
commercialized in the 1920s, peptide drugs have greatly reshaped our modern drug …

[HTML][HTML] Predictors of Inappropriately Rapid Coronary Lesion Progression in Patients Undergoing Percutaneous Coronary Interventions

G Sella, O Tuvali, M Welt, I Volodarsky, M Jaber… - CJC open, 2023 - Elsevier
Background Patients undergoing percutaneous coronary intervention (PCI) may experience
rapid atherosclerotic plaque progression in nontreated vessels that is unlikely to result from …

Anticoagulant Medications: A Comparative Review of Aspirin, Warfarin, Heparin, and Apixaban

HK Ibrahim, AM Mohammed… - … Sciences and Arts, 2024 - jurnal.itscience.org
Anticoagulant drugs play a role, in preventing and treating blood clotting disorders. This
article offers an in depth look at four prescribed anticoagulants; aspirin, warfarin, heparin …