Prevotella diversity, niches and interactions with the human host

A Tett, E Pasolli, G Masetti, D Ercolini… - Nature Reviews …, 2021 - nature.com
The genus Prevotella includes more than 50 characterized species that occur in varied
natural habitats, although most Prevotella spp. are associated with humans. In the human …

[HTML][HTML] Multi-omics data integration considerations and study design for biological systems and disease

S Graw, K Chappell, CL Washam, A Gies, J Bird… - Molecular omics, 2021 - pubs.rsc.org
With the advancement of next-generation sequencing and mass spectrometry, there is a
growing need for the ability to merge biological features in order to study a system as a …

[HTML][HTML] Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

A Blanco-Míguez, F Beghini, F Cumbo, LJ McIver… - Nature …, 2023 - nature.com
Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

[HTML][HTML] Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases

G Ianiro, M Punčochář, N Karcher, S Porcari… - Nature Medicine, 2022 - nature.com
Fecal microbiota transplantation (FMT) is highly effective against recurrent Clostridioides
difficile infection and is considered a promising treatment for other microbiome-related …

[HTML][HTML] Reconstruction of ancient microbial genomes from the human gut

MC Wibowo, Z Yang, M Borry, A Hübner, KD Huang… - Nature, 2021 - nature.com
Loss of gut microbial diversity–in industrial populations is associated with chronic diseases,
underscoring the importance of studying our ancestral gut microbiome. However, relatively …

[HTML][HTML] The person-to-person transmission landscape of the gut and oral microbiomes

M Valles-Colomer, A Blanco-Míguez, P Manghi… - Nature, 2023 - nature.com
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …

[HTML][HTML] Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome

MG Durrant, A Fanton, J Tycko, M Hinks… - Nature …, 2023 - nature.com
Large serine recombinases (LSRs) are DNA integrases that facilitate the site-specific
integration of mobile genetic elements into bacterial genomes. Only a few LSRs, such as …

[HTML][HTML] Expanded catalog of microbial genes and metagenome-assembled genomes from the pig gut microbiome

C Chen, Y Zhou, H Fu, X Xiong, S Fang, H Jiang… - Nature …, 2021 - nature.com
Gut microbiota plays an important role in pig health and production. Still, availability of
sequenced genomes and functional information for most pig gut microbes remains limited …

[HTML][HTML] Large-scale genome-wide analysis links lactic acid bacteria from food with the gut microbiome

E Pasolli, F De Filippis, IE Mauriello, F Cumbo… - Nature …, 2020 - nature.com
Lactic acid bacteria (LAB) are fundamental in the production of fermented foods and several
strains are regarded as probiotics. Large quantities of live LAB are consumed within …

Diversity and functional landscapes in the microbiota of animals in the wild

D Levin, N Raab, Y Pinto, D Rothschild, G Zanir… - Science, 2021 - science.org
Animals in the wild are able to subsist on pathogen-infected and poisonous food and show
immunity to various diseases. These may be due to their microbiota, yet we have a poor …