Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …

Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …

Malignant glioma constitutes one of the fatal primary brain tumors in adults. Such poor
prognosis calls for a better understanding of cancer-related signaling pathways of this …

MicroRNAs contribute to the development of kidney disease. Previous analyses of
microRNA expression in human kidneys, however, were limited by tissue heterogeneity or …

Insulin-like Growth Factor (IGF)/IGF-1 Receptor (IGF-1R) signaling is known to regulate stem
cell pluripotency and differentiation to trigger cell proliferation, organ development, and …

Background Triple negative breast cancer (TNBC) is an immunogenically hot tumor. The
immune checkpoint blockades (ICBs) have been recently emerged as promising therapeutic …

Hepatocellular carcinoma (HCC) is considered one of the greatest challenges to human life
and is the most common form of liver cancer. Treatment of HCC depends on chemotherapy …

Triple‐negative breast cancer (TNBC) represents an aggressive breast cancer subtype.
Among young females, TNBC is the leading cause of cancer‐related mortalities. Recently …

Abstract Triple-Negative Breast Cancer (TNBC) is one of the most aggressive and hot BC
subtypes. Our research group has recently shed the light on the utility of natural compounds …

Historically, the long-held protein-centered bias has denoted 98% of the human genome as
'Junk'DNA. However, the current work has shifted the perception of such'junk'transcriptional …