Polyelectrolyte complexes: Mechanisms, critical experimental aspects, and applications
AD Kulkarni, YH Vanjari, KH Sancheti… - Artificial cells …, 2016 - Taylor & Francis
The polyelectrolyte complexes (PECs) are versatile formulations formed by electrostatic
interactions between oppositely charged biopolymers. PECs have been investigated widely …
interactions between oppositely charged biopolymers. PECs have been investigated widely …
[HTML][HTML] Best practices in current models mimicking drug permeability in the gastrointestinal tract-An UNGAP review
The absorption of orally administered drug products is a complex, dynamic process,
dependant on a range of biopharmaceutical properties; notably the aqueous solubility of a …
dependant on a range of biopharmaceutical properties; notably the aqueous solubility of a …
Molecular engineering solutions for therapeutic peptide delivery
Proteins and their interactions in and out of cells must be well-orchestrated for the healthy
functioning and regulation of the body. Even the slightest disharmony can cause diseases …
functioning and regulation of the body. Even the slightest disharmony can cause diseases …
Development of nanomaterials for bone-targeted drug delivery
Highlights•The most representative nanomaterials for bone drug delivery are summarized.•
Nanomaterials can target bone by oral, implant, injectable, and transdermal …
Nanomaterials can target bone by oral, implant, injectable, and transdermal …
Oral delivery of therapeutic proteins and peptides: a review on recent developments
S Gupta, A Jain, M Chakraborty, JK Sahni, J Ali… - Drug …, 2013 - Taylor & Francis
Advent of recombinant technology in protein synthesis has given birth to a new range of
biopharmaceuticals. These therapeutic peptides and proteins are now emerging as an …
biopharmaceuticals. These therapeutic peptides and proteins are now emerging as an …
Lipid-based nanosuspensions for oral delivery of peptides, a critical review
Peptides are therapeutic molecules that can treat selectively and efficiently a wide range of
pathologies. However, their intrinsic properties cause their rapid degradation in the human …
pathologies. However, their intrinsic properties cause their rapid degradation in the human …
Polyelectrolyte complexes as prospective carriers for the oral delivery of protein therapeutics
V Bourganis, T Karamanidou, O Kammona… - European Journal of …, 2017 - Elsevier
The oral administration of protein therapeutics is hindered by the multitude of barriers
confronted by these molecules along the gastrointestinal tract (ie, acidic environment …
confronted by these molecules along the gastrointestinal tract (ie, acidic environment …
Synthesis of new thermo/pH sensitive drug delivery systems based on tragacanth gum polysaccharide
In this study, new pH/temperature responsive graft copolymers were synthesized based on
natural Tragacanth Gum (TG) carbohydrate and their controlled drug release was …
natural Tragacanth Gum (TG) carbohydrate and their controlled drug release was …
Amino-modified cellulose nanocrystals with adjustable hydrophobicity from combined regioselective oxidation and reductive amination
The controlled revision of surface properties to alter the hydrophobic features of
nanocellulose is a potential technique to obtain materials for many novel applications and to …
nanocellulose is a potential technique to obtain materials for many novel applications and to …
Oral drug delivery research in Europe
RJ Mrsny - Journal of controlled release, 2012 - Elsevier
The oral delivery of drugs is considered by decision-makers in the pharmaceutical industry
to be the most appealing route of administration. This belief has led to the identification of …
to be the most appealing route of administration. This belief has led to the identification of …