Solubility of ibrutinib in supercritical carbon dioxide (Sc-CO2): Data correlation and thermodynamic analysis

G Sodeifian, L Nasri, F Razmimanesh… - The Journal of Chemical …, 2023 - Elsevier
Abstract Ibrutinib (PCI-32765), marketed under the trade name IMBRUVICA, is a first-in-
class irreversible inhibitor drug of Bruton tyrosine kinase (BTK). In the current research, its …

Ibrutinib-Related Uveitis in Non-Hodgkin Lymphoma Patients: A Case Report and Literature Review

R Mendez, JS Pineda-Sierra… - Ocular Immunology …, 2024 - Taylor & Francis
Purpose To report two cases of ibrutinib-related uveitis and review the literature to date.
Methods We report two cases of ibrutinib-related uveitis using CARE guidelines and review …

Impact of ibrutinib on inflammation in a mouse model of Graves' orbitopathy

C Kim, JH Park, YJ Choi, HO Jun, JK Chung… - Frontiers in …, 2024 - frontiersin.org
Introduction Bruton's tyrosine kinase (BTK) and interleukin (IL)-2 Inducible T-cell Kinase
(ITK) inhibitors have anti-inflammatory properties. We investigated the therapeutic effect of …

[HTML][HTML] Bilateral panuveitis and exudative retinal detachments associated with alpelisib

YJ Chong, M Azzopardi, MO Tallouzi… - Case Reports in …, 2022 - karger.com
We report a case of alpelisib-induced uveitis. A 68-year-old female who had recently been
given alpelisib for metastatic breast cancer presented with a 2-week history of bilateral …

A Multidisciplinary Approach to Managing BTK Inhibitor Toxicity in Lymphoma and Chronic Lymphocytic Leukemia

JL Muñoz, JC Chavez, EM Sotomayor, JC Barrientos… - 2023 - Springer
Bruton tyrosine kinase inhibitors (BTKi) have transformed the treatment paradigm of patients
with B-cell lymphomas. In recent years, studies of BTKi have demonstrated superior efficacy …

Ibrutinib-Related Uveitis: A Case Series from Two Tertiary Centres in the United Kingdom

H Ibrahim, CS Chean, AJM Kalakonda… - Ocular Immunology …, 2024 - Taylor & Francis
Purpose Ibrutinib is an irreversible Bruton's tyrosine kinase inhibitor that disrupts B-cell
receptor signalling. It is licensed for treatment of low-grade B-cell malignancies, including …

Late Presentation of Pseudophakic Macula Edema from Oral Kinase Inhibitors: A Case Series and Literature Review

C Raj, L Levitz - Case Reports in Ophthalmology, 2024 - karger.com
Introduction: Two cases of late presentation (> 5 years) of bilateral pseudophakic macula
edema related to oral tyrosine kinase inhibitors are described. These cases are the first of …

Spontaneous Hyphema during Ibrutinib Treatment in a CLL Patient

KAT Aldecoa, CSL Macaraeg, A Dadlani… - Case Reports in …, 2023 - Wiley Online Library
Ibrutinib is an oral, first‐line, targeted therapy for chronic lymphocytic leukemia (CLL).
Commonly reported adverse events are diarrhea, fatigue, and musculoskeletal pain, but …

Alirocumab-associated unilateral posterior uveitis

ES Inegbedion, M Azzopardi, T Inessa… - BMJ Case Reports …, 2024 - casereports.bmj.com
A man in his mid-40s who had been recently started on alirocumab (a human monoclonal
antibody which inhibits proprotein convertase subtilisin/kexin type 9) due to his strong …

[PDF][PDF] Late Presentation of Pseudophakic Macula Edema from Oral Kinase Inhibitors: A Case Series and Literature

CRL Levitz - 2024 - scienceopen.com
Introduction: Two cases of late presentation (> 5 years) of bilateral pseudophakic macula
edema related to oral tyrosine kinase inhibitors are described. These cases are the first of …