Molecular pathways of major depressive disorder converge on the synapse
GR Fries, VA Saldana, J Finnstein, T Rein - Molecular Psychiatry, 2023 - nature.com
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …
molecular etiology. Extensive studies at different molecular levels point to a high complexity …
Candidate biomarkers in psychiatric disorders: state of the field
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …
aid in objectively diagnosing patients and providing individualized treatment …
Major depressive disorder: advances in neuroscience research and translational applications
Z Li, M Ruan, J Chen, Y Fang - Neuroscience bulletin, 2021 - Springer
Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …
psychiatric disorders with a high economic burden. The etiology of depression is still not …
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders
Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …
preclinical models and clinical studies of depression have revealed an array of structural …
Replicable brain–phenotype associations require large-scale neuroimaging data
Numerous neuroimaging studies have investigated the neural basis of interindividual
differences but the replicability of brain–phenotype associations remains largely unknown …
differences but the replicability of brain–phenotype associations remains largely unknown …
Ketamine and the neurobiology of depression: Toward next-generation rapid-acting antidepressant treatments
JH Krystal, AP Kaye, S Jefferson… - Proceedings of the …, 2023 - National Acad Sciences
Ketamine has emerged as a transformative and mechanistically novel pharmacotherapy for
depression. Its rapid onset of action, efficacy for treatment-resistant symptoms, and …
depression. Its rapid onset of action, efficacy for treatment-resistant symptoms, and …
The effect of social capital in mitigating drought impacts and improving livability of Iranian rural households
M Savari, HE Damaneh, HE Damaneh - International Journal of Disaster …, 2023 - Elsevier
The improvement of rural households' livability in drought conditions has always been an
important challenge for all countries, especially developing countries, because consecutive …
important challenge for all countries, especially developing countries, because consecutive …
Glutamate and GABA homeostasis and neurometabolism in major depressive disorder
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
Structural brain correlates in major depression, anxiety disorders and post-traumatic stress disorder: A voxel-based morphometry meta-analysis
The high comorbidity of Major Depressive Disorder (MDD), Anxiety Disorders (ANX), and
Posttraumatic Stress Disorder (PTSD) has hindered the study of their structural neural …
Posttraumatic Stress Disorder (PTSD) has hindered the study of their structural neural …