Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial
amount of research has been conducted to date to establish the anticancer potential of BBR …

Alkaloids are one of the most important classes of plant bioactives. Among these
isoquinoline alkaloids possess varied structures and exhibit numerous biological activities …

The phenylalanine–tyrosine–dopa–dopamine pathway provides dopamine to the brain. In
this process, tyrosine hydroxylase (TH) is the rate-limiting enzyme that hydroxylates tyrosine …

Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Berberine is a natural pentacyclic isoquinoline alkaloid that has been isolated as the
principal component of many popular medicinal plants such as the genus Berberis, Coptis …

Barberry (Berberis vulgaris L.) has different medicinal applications in folk medicine of Iran.
Berberine, an alkaloid constituent of this plant, is present in the roots, rhizomes, stem, and …

The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

Abstract Berberine (BBR), a naturally-occurring isoquinoline alkaloid isolated from several
Chinese herbal medicines, has been widely used for the treatment of dysentery and colitis …

Abstract Trimethylamine-N-oxide (TMAO) derived from the gut microbiota is an atherogenic
metabolite. This study investigates whether or not berberine (BBR) could reduce TMAO …

Berberine, a bioactive alkaloid isolated from several herbal substances, possesses multiple
pharmacological effects, including antimicrobial, antidiabetic, anticancer activities …