[HTML][HTML] Assessing the relative efficacy of interleukin-17 and interleukin-23 targeted treatments for moderate-to-severe plaque psoriasis: a systematic review and …

LM Sawyer, K Malottki, C Sabry-Grant, N Yasmeen… - PloS one, 2019 - journals.plos.org
Introduction New generation biologics, including interleukin (IL)-17 and IL-23 inhibitors,
have delivered higher rates of skin clearance than older treatments in head-to-head studies …

Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled …

KB Gordon, B Strober, M Lebwohl, M Augustin… - The Lancet, 2018 - thelancet.com
Background Risankizumab is a humanised IgG1 monoclonal antibody that binds to the p19
subunit of interleukin-23, inhibiting this key cytokine and its role in psoriatic inflammation …

Unmet needs in the field of psoriasis: pathogenesis and treatment

WH Boehncke, NC Brembilla - Clinical reviews in allergy & immunology, 2018 - Springer
In times of targeted therapies, innovative therapeutics become tools to further unravel the
pathogenesis of the treated disease, thus influencing current pathogenetic concepts. Based …

Efficacy and safety of risankizumab vs. secukinumab in patients with moderate‐to‐severe plaque psoriasis (IMMerge): results from a phase III, randomized, open‐label …

RB Warren, A Blauvelt, Y Poulin, S Beeck… - British Journal of …, 2021 - academic.oup.com
Background Patients with plaque psoriasis treated with biologic therapies need more
efficacious, safe and convenient treatments to improve quality of life. Risankizumab and …

Bimekizumab for the treatment of moderate‐to‐severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa …

R Oliver, JG Krueger, S Glatt, P Vajjah… - British journal of …, 2022 - academic.oup.com
Background Bimekizumab is a monoclonal antibody that selectively inhibits both interleukin
(IL)‐17A and IL‐17F, which is currently under investigation for treatment of moderate‐to …

[HTML][HTML] Risankizumab for the treatment of moderate-to-severe psoriasis: real-life multicenter experience from the Czech Republic

S Gkalpakiotis, P Cetkovska, P Arenberger… - Dermatology and …, 2021 - Springer
Introduction Risankizumab has been approved for the treatment of moderate-to-severe
plaque psoriasis; however, real-life data are limited. Our objectives were to evaluate the …

Hidradenitis suppurativa: new insights into disease mechanisms and an evolving treatment landscape

JG Krueger, J Frew, GBE Jemec… - British Journal of …, 2024 - academic.oup.com
Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic disabling and
debilitating inflammatory disease with a high unmet medical need. The prevalence of HS …

[HTML][HTML] Improving the management of psoriatic arthritis and axial spondyloarthritis: roundtable discussions with healthcare professionals and patients

M Garrido-Cumbrera, O Hillmann, R Mahapatra… - Rheumatology and …, 2017 - Springer
Psoriatic arthritis (PsA) and axial spondyloarthritis (AxSpA) are both chronic, inflammatory
conditions that result in a substantial burden of disease and reduced quality of life for …

Safety and efficacy of mirikizumab versus secukinumab and placebo in the treatment of moderate-to-severe plaque psoriasis (OASIS-2): a phase 3, multicentre …

K Papp, RB Warren, L Green, K Reich… - The Lancet …, 2023 - thelancet.com
Background Risankizumab and guselkumab, inhibitors of the interleukin (IL)-23 p19 subunit,
are approved for treatment of adult patients with moderate-to-severe plaque psoriasis, and …

Real-world evidence for ixekizumab in the treatment of psoriasis and psoriatic arthritis: literature review 2016–2021

A Reich, C Reed, C Schuster, C Robert… - Journal of …, 2023 - Taylor & Francis
Objectives To describe the results of a structured literature review of real-world outcomes
with ixekizumab in patients with psoriasis (PsO) and/or psoriatic arthritis (PsA). Methods …