An overview of recent advances in biomedical applications of click chemistry
J Kaur, M Saxena, N Rishi - Bioconjugate chemistry, 2021 - ACS Publications
Cu (I)-catalyzed azide–alkyne cycloaddition (CuAAC) is a modular and bio-orthogonal
approach that is being adopted for the efficient synthesis of organic and bioorganic …
approach that is being adopted for the efficient synthesis of organic and bioorganic …
Mono-and sesquiterpenes as a starting platform for the development of antiviral drugs
OI Yarovaya, NF Salakhutdinov - Russian Chemical Reviews, 2021 - iopscience.iop.org
The revies focuses on low-molecular-weight plant metabolites (mono-and sesquiterpenes)
exhibiting antiviral activity. Data on antiviral action of both essential oils and plant extracts …
exhibiting antiviral activity. Data on antiviral action of both essential oils and plant extracts …
Quinoline hydrazide/hydrazone derivatives: Recent insights on antibacterial activity and mechanism of action
Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
Synthesis, antimalarial and antioxidant activity of coumarin appended 1, 4-disubstituted 1, 2, 3-triazoles
CP Kaushik, M Chahal - Monatshefte für Chemie-Chemical Monthly, 2021 - Springer
A series of coumarin appended triazole hybrids of biotic interest was synthesized through
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …
click chemistry approach from the coumarin based terminal alkynes and aromatic azides. All …
Synthesis and in vitro study of artemisinin/synthetic peroxide‐based hybrid compounds against SARS‐CoV‐2 and cancer
L Herrmann, IA Yaremenko, A Çapcı, J Struwe… - …, 2022 - Wiley Online Library
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) cause
life‐threatening diseases in millions of people worldwide, in particular, in patients with …
life‐threatening diseases in millions of people worldwide, in particular, in patients with …
[HTML][HTML] Molecular insights into artemisinin resistance in Plasmodium falciparum: An updated review
WA Azmi, AFM Rizki, Y Djuardi, IM Artika… - Infection, Genetics and …, 2023 - Elsevier
Malaria still poses a major burden on human health around the world, especially in endemic
areas. Plasmodium resistance to several antimalarial drugs has been one of the major …
areas. Plasmodium resistance to several antimalarial drugs has been one of the major …
Autofluorescent Artemisinin‐Benzimidazole Hybrids via Organo‐Click Reaction: Study of Antiviral Properties and Mode of Action in Living Cells
L Herrmann, F Hahn, BW Grau, M Wild… - … A European Journal, 2023 - Wiley Online Library
Drug modification by a fluorescent label is a common tool for studying its mechanism of
action with fluorescence microscopy techniques. However, the attachment of a fluorescent …
action with fluorescence microscopy techniques. However, the attachment of a fluorescent …
Combinatorial drug treatments reveal promising anticytomegaloviral profiles for clinically relevant pharmaceutical kinase inhibitors (PKIs)
M Wild, J Kicuntod, L Seyler, C Wangen… - International journal of …, 2021 - mdpi.com
Human cytomegalovirus (HCMV) is a human pathogenic herpesvirus associated with a
variety of clinical symptoms. Current antiviral therapy is not always effective, so that …
variety of clinical symptoms. Current antiviral therapy is not always effective, so that …
Cyclodextrin-based multifunctional supramolecular catalysts for aqueous CuAAC reaction
J Li, X Feng, W Wang, M Guo, J Yang, X Li… - Applied Catalysis A …, 2023 - Elsevier
As an excellent bioorthogonal reaction, CuAAC reaction has been widely used in biological
research. In this work, three cyclodextrin derivatives β-CD-3, β-CD-4 and CD-P were …
research. In this work, three cyclodextrin derivatives β-CD-3, β-CD-4 and CD-P were …
Nanometals: As click catalysts for 1, 4-triazole cycloaddition (2020-till date)
In recent years, the search for efficient and sustainable catalysts for click chemistry has
gained significant attention. The process of copper-catalyzed azide-alkyne cycloaddition …
gained significant attention. The process of copper-catalyzed azide-alkyne cycloaddition …